NCT07703891Recruiting
Evaluating the Impact of Using the B-OK Bottles for HIV and ART Literacy in South Africa
Source: ClinicalTrials.gov · Last updated 27 Aug 2026
Brief summary (registry, in English)
Consistent use of antiretroviral therapy (ART) is essential for achieving suppression among people with HIV (PWH). Yet despite improvements in access to ART and improving viral suppression rates, an estimated one-third of PWH globally do not take ART as prescribed, thus allowing the virus to remain detectable and transmissible. This study tests whether a low-cost visual education tool, B-OK bottles, improves understanding of HIV, antiretroviral therapy (ART), and the concept of Undetectable = Untransmittable (U=U) among adults in Gauteng, South Africa using a randomized trial. Participants will be randomly assigned to one of three groups: (1) standard-of-care verbal information based on Department of Health guidelines, (2) information delivered in person using B-OK bottles, or (3) information delivered via a video demonstrating the B-OK bottles. The study will compare the two intervention formats to standard care, and to each other, to assess whether the tool improves knowledge, attitudes, and intentions related to HIV treatment and prevention, and whether the intervention results depend on delivery mode (in-person vs. video). Outcomes will be measured at baseline, immediately after the intervention, and at six-week follow-up.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 600 (estimated)
- First submitted
- 8 Jul 2026
- Start date
- 27 Jul 2026
- Primary completion date
- Sept 2026
- Lead sponsor
- University of Pennsylvania
- Diseases
- HIV
- NCT number
- NCT07703891
What you commit to
- Study type: Interventional
- Planned participants: 600
- From 27 Jul 2026 to the primary completion date, Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Unwilling or unable to provide written informed consent for study participation
Who the study is looking for
- Aged 18 years or older
- Residing in Gauteng
- Able to understand and communicate in English or another study-supported language
- Willing to attend an in-person study visit at the HE2RO offices
- Willing to provide contact details for follow-up at six weeks
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand Coordinator of this site? Confirm its status | Johannesburg | South Africa | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.