NCT07705178Recruiting
More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
"MaximALL" More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
In this study, we investigate the cardiopulmonary health of survivors who underwent cancer treatment for acute lymphoblastic leukemia (ALL) or lymphoma during childhood, compared with healthy controls. Modern imaging techniques (MRI, MSOT, and echocardiography) as well as questionnaires assessing cardiopulmonary and mental health are used.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- First submitted
- 9 Jul 2026
- Start date
- 1 Jul 2026
- Primary completion date
- 31 May 2028
- Lead sponsor
- University of Erlangen-Nürnberg Medical School
- NCT number
- NCT07705178
What you commit to
- Study type: Interventional
- Planned participants: 180
- From 1 Jul 2026 to the primary completion date, 31 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous lung surgery
- Previous lung surgery
- Previous lung surgery
Other illness
- Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure)
- General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.)
- Survivors of ALL:
- Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure)
- General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.)
- Survivors of Lymphoma:
- Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure)
- General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.)
Other
- Pregnancy, Lactation
- Known pleural or pericardial effusion
- Marked thoracic deformities/malformations
- Injuries that do not allow physical stress diagnostics
- Rejection of MRI imaging
- Pregnancy, Lactation
- Known pleural or pericardial effusion
- Marked thoracic deformities/malformations
- Injuries that do not allow physical stress diagnostics
- Rejection of MRI imaging
- Pregnancy, Lactation
- Known pleural or pericardial effusion
- Marked thoracic deformities/malformations
- Injuries that do not allow physical stress diagnostics
- Rejection of MRI imaging
Who the study is looking for
- no cancer diagnosis
- no lung diseases
- no vascular diseases
- No subjective reduction in physical performance
- age \>/= 18 years
- Completed therapy for ALL
- age \>/= 3 years
- Completed therapy for lymphoma
- age \>/= 3 years
Criteria the registry did not label
- Control Group:
Age in the registry: 3 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Pediatrics and Adolescent Medicine Coordinator of this site? Confirm its status | Erlangen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.