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NCT07706582Active, not recruitingPhase 2

Management of Iron Deficiency Anemia in Hemodialysis Patients

Evaluating the Therapeutic Impact of Lactoferrin on Complications in Patients With End-Stage Renal Disease

Source: ClinicalTrials.gov · Last updated 30 Oct 2026

Brief summary (registry, in English)

The aim of this interventional study is to assess the effectiveness of oral lactoferrin in improving hemoglobin levels and correcting iron deficiency anemia in patients with end-stage renal disease (ESRD) on dialysis and also evaluate the impact of lactoferrin on bone health by measuring serum calcium and phosphate and other bone health indicators. The participants will be divided into 3 groups as follow * The Lactoferrin group will receive treatment of oral lactoferrin at a dose of 100 mg twice daily alongside erythropoiesis-stimulating agent (ESA) therapy for three months. * The IV Iron group will receive IV Iron therapy with ESA for the same duration * The Lactoferrin + IV Iron group will receive both oral lactoferrin at a dose of 100 mg twice daily and IV Iron therapy alongside erythropoiesis-stimulating agent (ESA) therapy for three months.

Status (registry)
Active, not recruiting
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
108 (actual)
First submitted
11 Jul 2026
Start date
2 Nov 2025
Primary completion date
Dec 2026
Lead sponsor
Beni-Suef University
NCT number
NCT07706582

What you commit to

  • Study type: Interventional · Phase 2
  • Participants enrolled: 108
  • From 2 Nov 2025 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Active infection
  • Recent bleeding and recent blood transfusion
  • Patients with decompensated medical conditions

Other

  • Inflammation (any cause other than CKD)

Who the study is looking for

  • Adult patients aged over 18
  • Diagnosed with chronic kidney disease (CKD) on maintenance hemodialysis (3 sessions/week).
  • Diagnosed with functional iron deficiency anemia

Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Theodor Bilharz Research Institute (TBRI)
Coordinator of this site? Confirm its status
GizaEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.