NCT07706647Recruiting
Oil Pulling Reduction
Evaluation of Oil Pulling Mouthwash for Reduction of Dental Plaque, Gingivitis, and Selective Reduction of Bacteria
Source: ClinicalTrials.gov · Last updated 24 Aug 2026
Brief summary (registry, in English)
The goal of this study is to scientifically evaluate the efficacy of this oil pulling oral rinse in reducing dental plaque, gingival inflammation, gingival bleeding, and selectively reducing caries- and periodontal disease-associated bacteria compared to a marketed mouthwash and a placebo oral rinse
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 11 Jul 2026
- Start date
- 8 Jul 2026
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- NCT number
- NCT07706647
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 8 Jul 2026 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pacemaker or internal defibrillator, or any other active electrical implant anywhere in the body.
- Any surgery or recent dental procedure in the oral cavity within 3 months prior to treatment, or before complete healing.
- Habitual use of alcohol or drugs that may affect compliance or oral health
Other illness
- Current or history of oral cavity cancer or oropharyngeal cancer.
- Subject with destructive periodontal disease or those on antibiotic or anti-inflammatory drugs.
- Known allergic reaction to any of the study mouthwashes or any of their component.
- Any active condition, including but not limited to advanced periodontal disease or severe gingival recession, in the oral cavity at the discretion of the investigator.
- Any condition that might make it unsafe for the subject to participate in this study, at the discretion of the investigator.
- History of allergy or hypersensitivity to mouthwash ingredients
- Significant medical conditions, such as uncontrolled diabetes or immunosuppressive disorders
Other
- Pregnant or nursing by subject report.
- Subjects that do not brush regularly.
- Use of tobacco products, including cigarettes and smokeless tobacco
- Presence of orthodontic appliances, except for removable retainers
- Participation in another clinical trial within the last 30 days.
- Individuals unable to comply with study requirements, such as regular product use or scheduled visits.
Who the study is looking for
- Adult subjects aged 18-70, that are in good health.
- Subject must have:
- Baseline gingival inflammation (MGI) score of at least 1.80.
- Baseline gingival bleeding (GBI) score of ≥ 1 on at least 20 sites.
- An overnight (12 to 18 hour abstention from any oral hygiene) dental plaque (mean) score greater than 0.6 according to the RMNPI Index.
- Have a minimum of 20 'scorable' teeth (excluding 3rd molars).
- The subjects should understand the information provided about the investigative nature of the treatment, possible benefits and side effects. Subjects will sign the Informed Consent Form.
- The subjects should be willing to comply with the study procedure and schedule, including the follow-up visits.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Research Facility of the Center for Oral Health and Research, UTHSA Coordinator of this site? Confirm its status | San Antonio | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.