NCT07707544Active, not recruiting
Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management
Neurosurgery Resident
Source: ClinicalTrials.gov · Last updated 21 Jul 2026
Brief summary (registry, in English)
Several studies have investigated factors associated with visual deterioration in BIIP patients. Severe papilledema, delayed diagnosis, high CSF opening pressure, obesity, and visual field defects have been associated with poor prognosis. Optical Coherence Tomography has emerged as a valuable tool for monitoring retinal nerve fiber layer changes and detecting optic nerve damage. MRV abnormalities, particularly transverse sinus stenosis, have also gained increasing attention. Recent literature emphasizes the importance of multidisciplinary management involving neurosurgeons, neurologists, ophthalmologists, and radiologists.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 11 Jul 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Sohag University
- Diseases
- High blood pressure
- NCT number
- NCT07707544
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 1 Jun 2026 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous optic nerve diseases.
- Pregnancy (due to restricted medication options like Topiramate).
- Previous intracranial surgery or CSF shunting procedures
Other illness
- Cerebral venous sinus thrombosis.
- Severe systemic illness affecting vision.
Other
- Intracranial space occupying lesions.
Who the study is looking for
- •Patients fulfilling modified Dandy criteria.
- Age above 18 years.
- Confirmed diagnosis of IIH:
- Elevated opening pressure on lumbar puncture (\>25 cm H2o) in lateral decubitus position).
- Unremarkable neuroimaging (MRI/MRV) ruling out mass lesions, hydrocephalus, or venous sinus thrombosis.
- Presence of papilledema documented by a neuro-ophthalmologist.
Age in the registry: 18 months to 60 months · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sohag University Coordinator of this site? Confirm its status | Sohag | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.