NCT07707583Enrolling by invitation
Heart Rate Variability and Medication Adherence in Resistant Hypertension
Eart Rate Variability, Medication Adherence, and Blood Pressure Control in Resistant Hypertension: A Cross-Sectional Study
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in patients with resistant hypertension. Patients are recruited opportunistically, in a nurse-led manner, in a one-day-care cardiology unit, and undergo a single examination: a short-term HRV recording (Polar H10), a single blood draw for antihypertensive drug levels, office blood pressure, and self-completed questionnaires. There is no follow-up.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 13 Jul 2026
- Start date
- 26 Oct 2026
- Primary completion date
- 26 Nov 2027
- Lead sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
- Diseases
- High blood pressure
- NCT number
- NCT07707583
What you commit to
- Study type: Observational
- Planned participants: 150
- From 26 Oct 2026 to the primary completion date, 26 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Absence of sinus rhythm: atrial fibrillation/flutter, ventricular arrhythmias, higher-degree AV block, pacemaker/ICD with sustained pacing, sustained SVT, or significant ectopy
- Secondary hypertension
- Cognitive impairment precluding informed consent
Other
- Pregnancy or breastfeeding
Who the study is looking for
- Age 18-75 years with diagnosed essential hypertension
- Treated with ≥3 antihypertensive drugs of different classes, including ≥1 diuretic (resistant hypertension)
- Sinus rhythm
- Able to give informed consent and understand Czech
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nemocnice AGEL Třinec-Podlesí a.s. Coordinator of this site? Confirm its status | Třinec | Czechia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.