NCT07711821Recruiting
PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care
PRIMARY-HF: Diagnóstico de Insuficiência Cardíaca em Cuidados de Saúde Primários Utilizando Ecografia Point-of-Care e Péptidos Natriuréticos
Source: ClinicalTrials.gov · Last updated 17 Jul 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected heart failure or cardiovascular risk factors in primary care settings. The main questions it aims to answer are: * Does the use of NT-proBNP and/or POCUS increase the rate of new heart failure diagnoses compared with standard care? * Does this approach support earlier initiation of guideline-directed medical therapy and improve patients' quality of life? Researchers will compare standard care alone with standard care combined with NT-proBNP testing, POCUS, or both, to assess their impact on diagnosis and management of heart failure. Participants will: * Be randomly assigned to one of four groups (standard care, NT-proBNP, POCUS, or both). * Undergo clinical evaluation for heart failure according to their assigned group. * Be followed for 12 months with periodic assessments of quality of life and treatment adherence.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 160 (estimated)
- First submitted
- 13 Jul 2026
- Start date
- 23 Mar 2026
- Primary completion date
- Jul 2027
- Lead sponsor
- Universidade do Porto
- Diseases
- Heart failure
- NCT number
- NCT07711821
What you commit to
- Study type: Interventional
- Planned participants: 160
- From 23 Mar 2026 to the primary completion date, Jul 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known heart failure under active hospital-based follow-up
- Terminal illness or life expectancy \<1 year
- Severe comorbid conditions limiting participation or follow-up
Other
- Inability to provide informed consent
Who the study is looking for
- Adults aged ≥50 years
- Suspected heart failure (based on signs and/or symptoms) OR
- Presence of at least two cardiovascular risk factors, including:
- Diabetes mellitus
- Arterial hypertension
- Estimated glomerular filtration rate (eGFR) \<60 mL/min/1.73 m²
- Albuminuria
- Coronary artery disease or prior myocardial infarction or coronary revascularization
- Stroke or transient ischemic attack
- Atrial fibrillation or flutter
- Left ventricular hypertrophy or Q waves on electrocardiogram
- Obesity (body mass index ≥30 kg/m²)
- Ability to provide written informed consent
Age in the registry: 49 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Unidade de Saúde Familiar Conde da Lousã Coordinator of this site? Confirm its status | Amadora | Portugal | Not yet recruiting |
| Unidade de Saúde Familiar Rodrigues Miguéis Coordinator of this site? Confirm its status | Lisbon | Portugal | Not yet recruiting |
| Unidade de Saúde Familiar do Parque Coordinator of this site? Confirm its status | Lisbon | Portugal | Not yet recruiting |
| Unidade de Saúde Familiar Garcia Orta Coordinator of this site? Confirm its status | Porto | Portugal | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.