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NCT07713212Not yet recruitingPhase 4

Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis

Comparative Study of the Efficacy and Safety of Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis: A Pilot Randomized Controlled Clinical Trial

Source: ClinicalTrials.gov · Last updated 20 Jul 2026

Brief summary (registry, in English)

To assess whether adding fractional laser to topical corticosteroid improves treatment outcomes in palmoplanter psoriasis compared to topical corticosteroid alone.

Status (registry)
Not yet recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
32 (estimated)
First submitted
7 Jul 2026
Start date
15 Aug 2026
Primary completion date
15 Feb 2027
Lead sponsor
Cairo University
Diseases
Psoriasis
NCT number
NCT07713212

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 32
  • From 15 Aug 2026 to the primary completion date, 15 Feb 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Use of:
    • Systemic antipsoriatic therapy within 3 months
    • Biologic therapy within 12 weeks
    • Topical treatment on palms/soles within 2 weeks

Other illness

  • History of photosensitivity disorders

Other

  • Other palmoplantar dermatoses (eczema, tinea, keratoderma)
  • Generlized Pustular psoriasis
  • Erythrodermic psoriasis
  • Pregnancy or lactation

Who the study is looking for

  • Adults aged ≥18 years
  • Stable psoriasis
  • Confirmed cases of palmoplantar psoriasis (with or without psoriasis elsewhere) dermoscopically(Hand \_held dermoscopy) and histopathologically if required.
  • Willingness to comply with treatment and follow-up
  • Written informed consent obtained

Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cairo University
Coordinator of this site? Confirm its status
CairoEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.