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NCT07717866Active, not recruiting

Trifecta Research Study

Trifecta Research Study - An Observational Study Evaluating the Impact of Ibogaine-Magnesium, 5-MeO-DMT, Magnetic e-Resonance Therapy, and Physiological Supplementation in Special Operations Forces Combat Veterans

Source: ClinicalTrials.gov · Last updated 21 Jul 2026

Brief summary (registry, in English)

This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder (PTSD) and traumatic brain injury-related cognitive symptoms among Special Operations Forces (SOF) combat veterans.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
52 (actual)
First submitted
16 Jul 2026
Start date
1 Aug 2022
Primary completion date
1 Feb 2026
Lead sponsor
Axial Therapeutic Research
Diseases
Depression
NCT number
NCT07717866

What you commit to

  • Study type: Observational
  • Participants enrolled: 52
  • From 1 Aug 2022 to the primary completion date, 1 Feb 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Refusal to taper off of selective serotonin reuptake inhibitor (SSRI) medication

Other illness

  • Diagnosis of Schizophrenia, Bipolar I or II disorder for which patient has been hospitalized or medicated, Depersonalization and/or Derealization Disorder
  • Cerebellar dysfunction, Epilepsy, Psychosis or acute confusional state, Dementia
  • History of heart failure or hypertrophic heart
  • Active blood clots (e.g., Pulmonary embolism, Deep vein thrombosis)
  • Major respiratory conditions (e.g., Emphysema, Cystic fibrosis)
  • Severe chronic gastrointestinal issues (e.g., bleeding ulcer, leaky gut syndrome)

Lab values

  • Prolonged corrected QT interval (QTc) Interval (450ms in males; 470ms in females)
  • Abnormal blood test results (e.g., potassium or magnesium outside normal range)

Other

  • Within 6 months of surgeries
  • Impaired kidney or liver function

Who the study is looking for

  • At least 18 years of age
  • Sponsored by SOC-F Program

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Axial Therapeutic Research
Coordinator of this site? Confirm its status
NorthridgeUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.