NCT07718178Active, not recruiting
Effect of Thoracic Mobilization in People With Central Obesity
Effect of Mulligan Thoracic Mobilization on Ventilatory Functions and Chest Wall Expansion in Central Obesity
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn whether Mulligan thoracic mobilization in extension improves ventilatory functions and chest wall expansion in adults with central obesity. It will also evaluate whether adding Mulligan thoracic mobilization to a low-carbohydrate diet and aerobic exercise provides greater benefits than diet and exercise alone. The main questions it aims to answer are: Does Mulligan thoracic mobilization improve ventilatory functions (FVC, FEV₁, FEV₁/FVC ratio, and MVV) in adults with central obesity? Does Mulligan thoracic mobilization improve chest wall expansion, functional capacity, and health-related quality of life? Researchers will compare Mulligan thoracic mobilization combined with a low-carbohydrate diet and aerobic exercise to a low-carbohydrate diet and aerobic exercise alone to determine whether the addition of thoracic mobilization improves respiratory outcomes. Participants will: Be randomly assigned to either the intervention group or the control group. Receive an individualized low-carbohydrate diet and supervised aerobic exercise for 8 weeks. Receive Mulligan thoracic mobilization in extension three times per week for 8 weeks if assigned to the intervention group. Undergo assessments of ventilatory functions, chest wall expansion, functional capacity, and quality of life before and after the intervention.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 14 Jul 2026
- Start date
- 25 Jul 2026
- Primary completion date
- 15 Dec 2026
- Lead sponsor
- Cairo University
- Diseases
- Obesity
- NCT number
- NCT07718178
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 25 Jul 2026 to the primary completion date, 15 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent thoracic spine or rib injury/surgery.
- Contraindications to manual therapy (e.g., osteoporosis, rib fractures, or spinal tumors).
- Use of medications that affect body weight or metabolism (e.g., corticosteroids, antipsychotics, weight loss drugs).
Other illness
- Diagnosed COPD, asthma, or other chronic respiratory diseases.
- Cardiovascular instability or uncontrolled hypertension.
- History of bariatric surgery (e.g., gastric sleeve, gastric bypass).
- Neurological or musculoskeletal conditions that limit mobility or exercise participation and interfere with gait.
- Any acute respiratory infections in the past 6 weeks.
Other
- Participation in any structured weight loss program or exercise regimen in the past 6 months.
Who the study is looking for
- Males aged 25-35 years.
- Presence of central obesity, defined as:
- Waist circumference ≥102 cm in males.
- Waist-hip ratio (WHR) ≥0.90 in males.
- BMI from 30-39.9 kg/m².
- Willing to comply with conventional physiotherapy (diet and exercise) and mobilization programs.
- Medically stable individuals with a restrictive lung pattern (Normal FEV₁/FVC ratio and FVC \< 80% of predicted).
- Low level physical activity (using the International Physical Activity Questionnaire-Short Version).
- Non-smokers.
Age in the registry: 25 years to 35 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Deraya University Coordinator of this site? Confirm its status | Minya | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.