NCT07719647Not yet recruiting
Ultrasound Assessment of Joint Health in Patients With Mild Hemophilia (Factor Levels 5-40%)
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
Currently, few recommendations exist for patients with mild hemophilia, who represent approximately 60% of the hemophilia population. This study aims to provide objective data on joint health in these patients, which are currently limited compared to those with moderate or severe hemophilia. The use of joint ultrasound in mild hemophilia could allow early, asymptomatic detection of joint damage, support tailored management including patient education, and ultimately improve quality of life. The study will also explore the correlation between coagulation factor levels (FVIII or FIX) and other indicators of joint health in France.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 17 Jul 2026
- Start date
- Feb 2027
- Primary completion date
- Feb 2028
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Haemophilia
- NCT number
- NCT07719647
What you commit to
- Study type: Interventional
- Planned participants: 150
- From Feb 2027 to the primary completion date, Feb 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient on prophylactic treatment, defined as at least one of the following:
- ≥5 factor concentrate injections per month for a period of more than 6 months o. Treatment with emicizumab o. Last factor concentrate injection within the past 28 days
Other illness
- Patient with uncontrolled chronic rheumatologic disease, such as rheumatoid arthritis, inflammatory spondyloarthropathies, or microcrystalline arthritis.
Other
- Patient with acquired hemophilia.
- Known pregnancy or breastfeeding.
- Patient deprived of liberty or under legal guardianship or conservatorship.
Who the study is looking for
- Adult (≥18 years old) with congenital mild hemophilia, defined as historical coagulation factor level \>5% and \<40% (FVIII or FIX).
- Affiliated with a social security system.
- Provided written informed consent to participate in the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Necker Enfants Malades Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.