NCT07720401Recruiting
The Effect of Intradialytic Exercise on Postural Abnormalities
Effects of Supervised Intradialytic Exercise Program on Postural Abnormalities in Maintenance Hemodialysis Patients: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving maintenance hemodialysis. Participants will be randomized to either supervised intradialytic exercise plus usual care or usual care alone. The exercise program will be performed three times per week during scheduled hemodialysis sessions and will include postural correction exercises, resistance-band strengthening, core stabilization, stretching, breathing exercises, and seated aerobic cycling. The primary outcome will be change in thoracic kyphosis angle from baseline to Week 12. Secondary outcomes will include craniovertebral angle, balance, mobility, functional exercise capacity, gait speed, physical activity level, adherence, and adverse events. The findings may provide preliminary evidence on the feasibility, safety, and potential clinical value of incorporating postural correction exercises into routine hemodialysis care.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 98 (estimated)
- First submitted
- 17 Jul 2026
- Start date
- 25 Aug 2026
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Pardis Specialized Wellness Institute
- Diseases
- Chronic kidney disease
- NCT number
- NCT07720401
What you commit to
- Study type: Interventional
- Planned participants: 98
- From 25 Aug 2026 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Hemodynamic instability defined as systolic blood pressure \<90 mmHg or \>200 mmHg, or severe orthostatic hypotension, at screening or prior to exercise sessions
- Scheduled kidney transplantation within the study period
Other illness
- Unstable cardiovascular status, including recent (within 3 months) myocardial infarction, unstable angina, decompensated congestive heart failure (NYHA Class III-IV), or uncontrolled arrhythmia
- Active infection, acute febrile illness, or acute medical condition requiring hospitalization
- Severe peripheral neuropathy or vascular disease (ABI \<0.6) precluding lower limb exercise
- Severe cognitive impairment (MMSE \<18) preventing informed consent or adherence to exercise instruction
Lab values
- Uncontrolled diabetes mellitus with labile glycemic control (blood glucose \<4 mmol/L or \>22 mmol/L at dialysis session start)
Other
- Severe musculoskeletal pain at rest or with minimal activity (Numeric Pain Rating Scale ≥7/10) that would preclude exercise participation
- Inability to perform seated exercises, walk independently, or maintain upright posture; severe neurological disability
- Recent fracture (within 6 months) of vertebral column, pelvis, or lower extremities
- Dyspnea at rest or with activities of daily living corresponding to NYHA Class IV
- Participation in a structured exercise program targeting postural correction, resistance, or balance training ≥3 times per week in the preceding 3 months
- Pregnancy or planned pregnancy during the study period
- Life expectancy \<6 months as determined by the attending nephrologist
Who the study is looking for
- Age 18-80 years
- Diagnosed with ESRD and receiving stable maintenance hemodialysis for at least 3 months at the participating center, with a dialysis frequency of three sessions per week
- Confirmed presence of at least one postural abnormality (hyperkyphosis ≥53° in women or ≥55° in men, or CVA \<53°) assessed at screening
- Written informed consent obtained, indicating decision-making capacity and willingness to participate
- Medical clearance from attending nephrologist to participate in supervised exercise during dialysis
- Ability to sit upright in a dialysis chair and perform seated or supported standing exercises
- Ability to communicate in Persian and understand study instructions
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pardis specialized wellness institute Coordinator of this site? Confirm its status | Isfahan | Iran | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.