NCT07725211Recruiting
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
High-Repetition Task-Oriented Training Versus High-Intensity Gait Training for Lower Extremity Rehabilitation in Individuals With Chronic Stroke: An Assessor-Blinded Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke. Forty-five participants will be randomly assigned to one of three groups: (1) neurodevelopmental treatment (NDT) alone, (2) NDT combined with high-repetition task-oriented training, or (3) NDT combined with high-intensity gait training. All participants will receive treatment 3 days per week for 8 weeks (24 sessions in total). Walking capacity (6-Minute Walk Test) and functional mobility (Timed Up and Go Test, modified Dynamic Gait Index, 10-Meter Walk Test) will be assessed before and after the intervention by an assessor blinded to group allocation. The study hypothesizes that adding structured, intensity-based training approaches to conventional NDT will lead to greater improvements in walking capacity than NDT alone.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- First submitted
- 21 Jul 2026
- Start date
- 15 Aug 2026
- Primary completion date
- 15 Dec 2026
- Lead sponsor
- Istanbul University - Cerrahpasa
- Diseases
- Stroke
- NCT number
- NCT07725211
What you commit to
- Study type: Interventional
- Planned participants: 45
- From 15 Aug 2026 to the primary completion date, 15 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Recurrent stroke or bilateral hemispheric involvement
- Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise
- Orthopedic, rheumatological, or other neurological conditions affecting gait
- Severe visual or vestibular impairment
- Severe aphasia or cognitive impairment preventing participation in training or assessments
Other
- Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score \> 3)
- Participation in another structured rehabilitation or exercise program during the study period
- Botulinum toxin injection to the lower extremity within the last 6 months
Who the study is looking for
- Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and/or radiological findings
- Time since stroke onset of at least 6 months (chronic phase)
- Age between 18 and 75 years
- Ability to walk at least 10 meters independently, with or without an assistive device
- Functional Ambulation Category (FAC) score of 3 or higher
- Sufficient cognitive ability to understand and follow instructions (Mini-Mental State Examination score ≥ 24)
- Willingness to participate and provision of written informed consent
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bingol State Hospital - City: Bingöl, Country: Türkiye (listede "Turkey" olarak geçebilir), Zip: 12000 Coordinator of this site? Confirm its status | Bingoel | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.