Fact CheckerSign in

NCT07727135Not yet recruiting

Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation

Danish Randomized Trial of Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation

Source: ClinicalTrials.gov · Last updated 6 Aug 2026

Brief summary (registry, in English)

People with chest pain are often tested for a heart attack using a blood test called high-sensitivity cardiac troponin (hs-cTn). Traditionally, this blood test is repeated 3 hours after the first sample. Newer guidelines recommend repeating the test after 1 hour instead, which may allow patients to receive a diagnosis and leave the hospital sooner. The purpose of the DanRUSH trial is to compare these two strategies: repeating the blood test after 1 hour versus after 3 hours in adults with suspected acute coronary syndrome. The study will evaluate whether the 1-hour strategy is as safe as the 3-hour strategy while reducing the length of hospital stay. DanRUSH is a nationwide, pragmatic, cluster-randomized trial conducted in emergency- and cardiology departments across Denmark. The results will help determine the best timing for blood testing in patients with suspected heart attack and improve future care for these patients.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
28000 (estimated)
First submitted
7 Jul 2026
Start date
1 Sept 2026
Primary completion date
1 Sept 2028
Lead sponsor
Herlev and Gentofte Hospital
NCT number
NCT07727135

What you commit to

  • Study type: Interventional
  • Planned participants: 28000
  • From 1 Sept 2026 to the primary completion date, 1 Sept 2028
  • 11 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • ST-segment elevation myocardial infarction (STEMI) identified on the presenting electrocardiogram and requiring immediate reperfusion therapy.

Age

  • Age \<18 years.

Who the study is looking for

  • Adults (≥18 years) presenting with suspected acute coronary syndrome (ACS) with a clinical indication for high-sensitivity cardiac troponin testing

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Aalborg University Hospital
Coordinator of this site? Confirm its status
AalborgDenmarkUnknown status
Bispebjerg & Frederiksberg Hospital
Coordinator of this site? Confirm its status
BispebjergDenmarkUnknown status
Esbjerg Og Grindsted Sygehus
Coordinator of this site? Confirm its status
EsbjergDenmarkUnknown status
Gødstrup Regional Hospital
Coordinator of this site? Confirm its status
GødstrupDenmarkUnknown status
Herlev & Gentofte Hospital
Coordinator of this site? Confirm its status
HerlevDenmarkUnknown status
Nordsjællands Hospital
Coordinator of this site? Confirm its status
HillerødDenmarkUnknown status
Amager-Hvidovre Hospital
Coordinator of this site? Confirm its status
HvidovreDenmarkUnknown status
Nykøbing Falster County Hospital
Coordinator of this site? Confirm its status
Nykøbing FalsterDenmarkUnknown status
Odense University Hospital
Coordinator of this site? Confirm its status
OdenseDenmarkUnknown status
Svendborg Hospital
Coordinator of this site? Confirm its status
SvendborgDenmarkUnknown status
Central Jutland Regional Hospital (Viborg Hospital & Silkeborg Hospital)
Coordinator of this site? Confirm its status
ViborgDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.