NCT07727135Not yet recruiting
Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation
Danish Randomized Trial of Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital Presentation
Source: ClinicalTrials.gov · Last updated 6 Aug 2026
Brief summary (registry, in English)
People with chest pain are often tested for a heart attack using a blood test called high-sensitivity cardiac troponin (hs-cTn). Traditionally, this blood test is repeated 3 hours after the first sample. Newer guidelines recommend repeating the test after 1 hour instead, which may allow patients to receive a diagnosis and leave the hospital sooner. The purpose of the DanRUSH trial is to compare these two strategies: repeating the blood test after 1 hour versus after 3 hours in adults with suspected acute coronary syndrome. The study will evaluate whether the 1-hour strategy is as safe as the 3-hour strategy while reducing the length of hospital stay. DanRUSH is a nationwide, pragmatic, cluster-randomized trial conducted in emergency- and cardiology departments across Denmark. The results will help determine the best timing for blood testing in patients with suspected heart attack and improve future care for these patients.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 28000 (estimated)
- First submitted
- 7 Jul 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 1 Sept 2028
- Lead sponsor
- Herlev and Gentofte Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT07727135
What you commit to
- Study type: Interventional
- Planned participants: 28000
- From 1 Sept 2026 to the primary completion date, 1 Sept 2028
- 11 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- ST-segment elevation myocardial infarction (STEMI) identified on the presenting electrocardiogram and requiring immediate reperfusion therapy.
Age
- Age \<18 years.
Who the study is looking for
- Adults (≥18 years) presenting with suspected acute coronary syndrome (ACS) with a clinical indication for high-sensitivity cardiac troponin testing
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aalborg University Hospital Coordinator of this site? Confirm its status | Aalborg | Denmark | Unknown status |
| Bispebjerg & Frederiksberg Hospital Coordinator of this site? Confirm its status | Bispebjerg | Denmark | Unknown status |
| Esbjerg Og Grindsted Sygehus Coordinator of this site? Confirm its status | Esbjerg | Denmark | Unknown status |
| Gødstrup Regional Hospital Coordinator of this site? Confirm its status | Gødstrup | Denmark | Unknown status |
| Herlev & Gentofte Hospital Coordinator of this site? Confirm its status | Herlev | Denmark | Unknown status |
| Nordsjællands Hospital Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
| Amager-Hvidovre Hospital Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
| Nykøbing Falster County Hospital Coordinator of this site? Confirm its status | Nykøbing Falster | Denmark | Unknown status |
| Odense University Hospital Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
| Svendborg Hospital Coordinator of this site? Confirm its status | Svendborg | Denmark | Unknown status |
| Central Jutland Regional Hospital (Viborg Hospital & Silkeborg Hospital) Coordinator of this site? Confirm its status | Viborg | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.