NCT07727434Recruiting
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
Comparative Evaluation of Psychological Stress and Anxiety Levels Before Biopsy, After Diagnosis, and During Treatment in Patients With Suspected Primary or Metastatic Bone or Soft Tissue Malignancy
Source: ClinicalTrials.gov · Last updated 27 Jul 2026
Brief summary (registry, in English)
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue. The period before biopsy, the disclosure of pathology results, and the start of treatment may be associated with changing levels of psychological stress and anxiety. The purpose of the study is to compare psychological stress and anxiety in the same participants at three points in their care: before biopsy, after the pathology result or diagnosis is explained, and at treatment initiation. The investigators hypothesize that psychological questionnaire scores will differ across these three time points and may be associated with age, sex, disease stage, metastasis status, and treatment type. Participants will complete the Hospital Anxiety and Depression Scale, Perceived Stress Scale, and Distress Thermometer. The study team will also collect relevant demographic and routine clinical information from medical records. The study will not assign any biopsy, diagnostic procedure, or treatment. All diagnostic and treatment decisions will be made by the treating clinical team as part of routine care.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 20 Jul 2026
- Start date
- 20 Jul 2026
- Primary completion date
- 20 Dec 2026
- Lead sponsor
- Istanbul University
- Diseases
- Sarcoma
- NCT number
- NCT07727434
What you commit to
- Study type: Observational
- Planned participants: 100
- From 20 Jul 2026 to the primary completion date, 20 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of previous malignancy.
- Current serious psychiatric disorder, including major depressive disorder or psychotic disorder.
- Cognitive impairment or communication difficulty that prevents valid completion of the study questionnaires.
- Severe general medical condition or need for emergency intervention that makes study participation inappropriate.
Who the study is looking for
- Age 18 years or older.
- Scheduled for biopsy because of a suspected solid tumor.
- Able to understand and answer the study questionnaires.
- Able and willing to provide written informed consent before study participation.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Istanbul University, Istanbul Faculty of Medicine, Department of Orthopedics and Traumatology Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.