NCT07729787Recruiting
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
Comparative Effects of Autogenic Drainage and Mechanical Percussion on Lung Function, Dyspnea and Quality of Life in Children With Cystic Fibrosis
Source: ClinicalTrials.gov · Last updated 28 Jul 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis. The main questions it aims to answer are: * Does autogenic drainage improve lung function more effectively than mechanical percussion in children with cystic fibrosis? * Does autogenic drainage reduce dyspnea (breathlessness) more effectively than mechanical percussion? * Does autogenic drainage improve health-related quality of life more effectively than mechanical percussion? Researchers will compare autogenic drainage with mechanical percussion to determine which airway clearance technique provides greater benefits for children with cystic fibrosis. Participants will: * Be randomly assigned to receive either autogenic drainage or mechanical percussion therapy. * Participate in supervised treatment sessions five times per week for six weeks. * Undergo assessments of lung function using spirometry (FEV₁ and FVC), dyspnea using the Modified Borg Dyspnea Scale, and quality of life using the Cystic Fibrosis Questionnaire-Revised (CFQ-R) before and after the intervention period. The findings of this study may help identify the most effective airway clearance technique for improving respiratory health and quality of life in children with cystic fibrosis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 21 Jul 2026
- Start date
- Jun 2026
- Primary completion date
- Nov 2026
- Lead sponsor
- Riphah International University
- Diseases
- Cystic fibrosis
- NCT number
- NCT07729787
What you commit to
- Study type: Interventional
- Planned participants: 32
- From Jun 2026 to the primary completion date, Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of thoracic surgery.
Other
- Active hemoptysis.
- Severe physical or cognitive disabilities limiting participation in the intervention or assessments.
Who the study is looking for
- Confirmed diagnosis of cystic fibrosis (CF) through a sweat test or genetic testing.
- Age between 6 and 12 years.
- Clinically stable condition (no acute pulmonary exacerbation within the last 4 weeks).
Age in the registry: 6 years to 12 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nishter Hospital Multan Coordinator of this site? Confirm its status | Multan Khurd | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.