Fact CheckerSign in

NCT07730203Recruiting

Photon-Counting Computed Tomography-Based Urethral Visualization Without Catheterization for Radiotherapy Planning: A Prospective Pilot Study Under ANTHEM

Source: ClinicalTrials.gov · Last updated 28 Jul 2026

Brief summary (registry, in English)

In prostate cancer radiotherapy, it is important to accurately identify and protect healthy organs near the prostate. One of these structures is the urethra, the tube that carries urine from the bladder out of the body. If the urethra receives too much radiation, patients may experience urinary side effects. Current CT scans used for treatment planning do not clearly show the urethra unless a urinary catheter is inserted. While a catheter can improve visibility, it may cause discomfort, increase the risk of infection, and slightly change the natural position of the urethra. MRI scans can also help visualize the urethra, but they are not always available and may not fit easily into all treatment workflows. Photon-counting CT (PCCT) is a new type of CT scanner that produces higher-quality images with better detail. This technology may allow doctors to see the urethra without using a catheter. The purpose of this pilot study is to investigate whether PCCT can reliably visualize the urethra in prostate cancer patients without the need for catheter insertion. If successful, this approach could make treatment planning more comfortable and less invasive while helping doctors better protect healthy tissues during radiotherapy.

Status (registry)
Recruiting
Study type
Observational
Enrollment
20 (estimated)
First submitted
24 Jun 2026
Start date
22 Jun 2026
Primary completion date
31 Dec 2026
Lead sponsor
Istituto Clinico Humanitas
NCT number
NCT07730203

What you commit to

  • Study type: Observational
  • Planned participants: 20
  • From 22 Jun 2026 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Known urethral stricture or recent urethral surgery

Other illness

  • Active or suspected urinary tract infection.

Other

  • Contraindication to catheter placement.

Who the study is looking for

  • Prostate cancer candidate to radiotherapy
  • Written informed consent.
  • Eligibility for urethral catheter placement according to institutional practice

Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS Humanitas Research Hospital
Coordinator of this site? Confirm its status
RozzanoItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.