NCT07730255Active, not recruiting
Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity
The Impact of Physical Exercise Associated or Not With Taurine Supplementation on Intramuscular Fat Infiltration in Older Women With Obesity: A Transcriptomic and Metabolomic Approach
Source: ClinicalTrials.gov · Last updated 28 Jul 2026
Brief summary (registry, in English)
This randomized clinical trial aims to investigate the effects of multicomponent concurrent exercise training associated or not with taurine supplementation on intramuscular fat infiltration, physical performance, transcriptomic profile, and metabolomic profile in older women with obesity. Forty women aged 60 to 75 years with obesity will be randomized into four groups: control, exercise, taurine, and exercise plus taurine. The intervention will last 16 weeks. Outcomes include magnetic resonance imaging, body composition, muscle biopsy, blood biomarkers, functional capacity tests, transcriptomic analysis, and metabolomic analysis.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 44 (estimated)
- First submitted
- 21 May 2026
- Start date
- 1 May 2026
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Sao Paulo
- Diseases
- Obesity
- NCT number
- NCT07730255
What you commit to
- Study type: Interventional
- Planned participants: 44
- From 1 May 2026 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- infectious and contagious diseases,
- chronic kidney diseases,
Other
- alcohol consumption,
- smoking,
- undergoing weight loss treatment, and
- presenting a score ≤13 on cognitive screening using the Mini-Mental State Examination (MMSE).
Who the study is looking for
- Female,
- 60 and 75 years of age,
- Body mass lower than 120 kg,
- Be sedentary (not having engaged in physical exercise for at least 3 months), and
- Body Mass Index between 30 and 40 kg/m².
Age in the registry: 60 years to 75 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Escola de Educação Física e Esporte de Ribeirão Preto, Ribeirão Preto, São Paulo. Coordinator of this site? Confirm its status | Ribeirão Preto | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.