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NCT07732686Not yet recruiting

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

Breath Volatile Organic Compounds (VOC) Analysis Using Proton Transfer Reaction Mass Spectrometry (PTR-MS)

Source: ClinicalTrials.gov · Last updated 29 Jul 2026

Brief summary (registry, in English)

The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
2000 (estimated)
First submitted
23 Jul 2026
Start date
1 Oct 2026
Primary completion date
31 Oct 2027
Lead sponsor
University of Oklahoma
NCT number
NCT07732686

What you commit to

  • Study type: Observational
  • Planned participants: 2000
  • From 1 Oct 2026 to the primary completion date, 31 Oct 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Cancer patients who are on active treatment for cancer or have received cancer treatment within one month

Other illness

  • Active respiratory infection symptoms

Age

  • Under the age of 18.

Other

  • Anticipated inability to complete breath sampling procedure.
  • Unable to provide informed consent.
  • Pregnant women
  • Recent use of antibiotics
  • Difficulty in performing coached exhalation
  • Individuals who are unable to follow the instructions

Who the study is looking for

  • Age ≥ 18 at the time of consent. Male and female patients to be tested.
  • Capable of understanding written and/or spoken English language.
  • Able to provide informed consent.
  • Cancer of any type.
  • Newly diagnosed cancer and untreated or established diagnosis of cancer. For established cancer patients, no active anti-cancer treatment for more than one month (reasons for no treatment are such as relapse, progression of cancer, refractory, or intolerance to treatment etc.)

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
OU Health Stephenson Cancer Center
Coordinator of this site? Confirm its status
Oklahoma CityUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.