NCT07732894Recruiting
Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome
"The Effects of Aerobic Exercise and Guided Imagery on Low Anterior Resection Syndrome After Rectal Cancer Surgery: A Randomized Controlled Study"
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
Low Anterior Resection Syndrome (LARS) is a common complication after sphincter-preserving rectal cancer surgery and may negatively affect bowel function and quality of life. Although exercise has been shown to improve physical function and well-being in cancer survivors, evidence regarding its effects on LARS symptoms remains limited. This randomized controlled, multicenter study aims to evaluate the effects of an aerobic exercise program combined with guided imagery on bowel symptoms, quality of life, physical activity level, functional capacity, and psychological well-being in patients with LARS after rectal cancer surgery. Participants will be randomly assigned to either an intervention group receiving aerobic exercise and guided imagery in addition to standard care or a control group receiving standard care alone. Outcomes will be assessed at baseline and after the intervention period using validated clinical and patient-reported outcome measures. The findings of this study may contribute to the development of evidence-based rehabilitation strategies for improving bowel function and quality of life in patients with LARS following rectal cancer surgery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 15 Jul 2026
- Start date
- 30 Dec 2025
- Primary completion date
- 30 Dec 2026
- Lead sponsor
- Biruni University
- Diseases
- Colorectal cancer
- NCT number
- NCT07732894
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 30 Dec 2025 to the primary completion date, 30 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of incontinence or defecation disorder not related to rectal cancer
- Having another type of surgery for rectal cancer (Hartmann procedure, abdominoperineal excision, transanal endoscopic microsurgical resection, or sigmoid resection)
- Deterioration in general health, neurological disease and/or physical disability
- Inability to answer questions or make interventions due to mental disorder
Other
- BMI \> 30 kg/m2 (obese individuals)
Who the study is looking for
- Upper-Middle-Lower Rectal Cancer
- Having undergone surgery with TMJ
- Having a protective ileostomy and a closed stoma
- Being tumor-free according to laboratory reports (carcinoembryonic antigen), endoscopic findings, and abdominal ultrasonography and/or computed tomography data
- Having at least minor LARS scores ("between 21" and "42") according to the -LARS scoring questionnaire
- Having the ability to perform voluntary perineal traction contractions with perineal palpation
- Being a volunteer with informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Bahcelievler Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.