NCT07733427Not yet recruiting
Evaluating the Effectiveness of AIT in the Treatment of Pain Related to Pancreatic Cancer
A Pilot Study Aimed at Evaluating the Effectiveness of AIT in the Treatment of Pain Related to Pancreatic Cancer
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
The aim of this clinical trial is to assess the effectiveness of intratracheal analgesia on pain intensity in cancer patients, from the start of treatment up to 3 months. It will also investigate the safety of this technique. The main questions it seeks to answer are as follows: What is the impact on the use of opioid analgesics, and can this be measured? What is the quality of life? What is the quality of sleep, and can this be assessed? How does the patient's weight change? Is the patient satisfied? What is the patient's overall survival? The researchers will assess the equivalent daily dose of morphine (mg/day) between enrolment and follow-up visits, as well as the number of patients requiring an escalation of analgesic treatment. Overall quality of life score measured using the ESAS questionnaire between enrolment and follow-up visits; satisfaction assessed using a numerical satisfaction scale (0-10); sleep quality assessed using the ISI questionnaire; and the tolerability and safety of the technique assessed by monitoring adverse events. Eligible participants: Following implantation of the intrathecal pump, participants will have scheduled consultations at day 30, then at 3, 6, 9 and 12 months, with questionnaires to be completed.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 20 Jul 2026
- Start date
- Sept 2026
- Primary completion date
- Mar 2027
- Lead sponsor
- Clinique Bizet
- Diseases
- Pancreatic cancer
- NCT number
- NCT07733427
What you commit to
- Study type: Interventional
- Planned participants: 40
- From Sept 2026 to the primary completion date, Mar 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute respiratory infection
- Uncontrolled coagulation disorder
Age
- Patients under the age of 20.
Other
- Contraindications to intratracheal analgesia
- Pregnancy or breastfeeding
- Unable to comply with medical follow-up for the study.
- Adults who are legally protected, under guardianship or under a conservatorship
Who the study is looking for
- Subject aged over 20 years
- Patient with histologically confirmed pancreatic carcinoma
- Chronic cancer-related pain that is inadequately controlled by standard treatment or for whom analgesics are contraindicated.
- EMO \< 120 mg/day Patients experiencing side effects: sedation, vomiting, constipation, or an allergy to morphine.
- Signed informed consent
- Participants affiliated with or eligible for a social security scheme
- Agree to complete the various study questionnaires
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bizet Clinic Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Clinique Bizet Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Benkessou Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.