Perinatal Autism Genetics and Epigenetics Study

Other illness

• History of severe mental illness in the past year, resulting in inpatient admission
• History of serious neonatal complications requiring NICU admission for one week or more
• Known genetic or syndromic condition (e.g. Down Syndrome, etc.) that impacts learning and brain development
• Hearing impairment

Age

• \<35 weeks gestational age at birth
• ASD Group at age 18 to 27 months
  • \- None
• Developmental Delay (DD) Group at age 18 to 27 months
• Typically Developing (TD) Group at age 18 to 27 months

Other

• Criteria for Pregnant Women:
• Non-English speaking mother
• All children
• Screen positive for ASD (M-CHAT \>= 4 AND POSI \>= 3)
• First-degree relative who has been diagnosed with ASD
• Screen positive for ASD (M-CHAT \>= 4 AND POSI \>= 3)
• Developmental screening/assessment score in the "at risk" range.
• First-degree relative who has been diagnosed with ASD

• Criteria for Pregnant Women:
• Pregnant women in their 1st or 2nd trimester of a singleton pregnancy.
• Age 18 to 50 years
• Currently use a smart phone
• ASD Group at age 18 to 27 months
• M-CHAT score \>= 4 or POSI score \>= 3
• Child has subsequently clinically confirmed diagnosis of ASD, based on ADOS/TAP testing and/or other clinical evaluation
• Developmental Delay (DD) Group at age 18 to 27-months
• Developmental screening score on SWYC in the "at risk" range.
• Child has subsequently clinically confirmed developmental delay on clinical evaluation and/or self-report measure
• Typically Developing (TD) Group at age 18 to 27 months - None