NCT07740317Recruiting
Neurocognitive Trajectories After BCMA CAR-T
Longitudinal Neurocognitive Trajectories After BCMA CAR-T in Multiple Myeloma
Source: ClinicalTrials.gov · Last updated 23 Oct 2026
Brief summary (registry, in English)
The purpose of this research study is to evaluate cognitive changes over time in participants with relapsed or refractory multiple myeloma who have received chimeric antigen receptor T-cell therapy (CAR-T).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 28 Jul 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Nov 2029
- Lead sponsor
- Wake Forest University Health Sciences
- Diseases
- Multiple myeloma
- NCT number
- NCT07740317
What you commit to
- Study type: Observational
- Planned participants: 50
- From 1 Nov 2026 to the primary completion date, 30 Nov 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent investigational neuroactive drugs
Other illness
- Active central nervous system (CNS) disease
- Known neurodegenerative disease or major neurocognitive disorder
- Stroke and/or traumatic brain injury (TBI) within 12 months
Who the study is looking for
- Ability to understand and willingness to sign an IRB-approved informed consent
- Ability to retain independent decision-making capacity as per the enrolling investigator
- Age ≥ 18 years of age at the time of consent
- Scheduled to receive BCMA CAR-T therapy for RRMM as confirmed by the treating clinician
- Ability to read and understand the English language
- ECOG 0-2
- If actively taking benzodiazepine, must be able to hold for 3 hours prior to study assessments as per treating clinician
- Reliable access to internet access; a tablet, laptop and/or desktop computer with a camera; or willingness to come into the clinic to conduct study procedures as outlined in the Study Calendar- as per participant self-report
- Ability to complete required assessments, as determined by the treating clinician
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Atrium Health Levine Cancer Coordinator of this site? Confirm its status | Charlotte | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.