NCT07741357Not yet recruiting
Kidney RISE: Randomized Integrated Supportive CarE Trial
Phase II Multi-Site Randomized Controlled Trial Testing Integrated Kidney Palliative Care Compared With Usual Chronic Kidney Disease Care (Kidney RISE)
Source: ClinicalTrials.gov · Last updated 3 Aug 2026
Brief summary (registry, in English)
The purpose of study is to investigate whether adding palliative care to usual chronic kidney disease (CKD) care improves symptoms and quality of life for people with CKD. The primary objectives are to 1) determine efficacy of Kidney Palliative Care (KPC) integrated with CKD care on symptom burden compared with usual CKD care, 2) identify clinical and demographic factors associated with differential responses to KPC, and 3) characterize participant and provider experiences with kidney care and factors influencing implementation.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 280 (estimated)
- First submitted
- 29 Jul 2026
- Start date
- May 2027
- Primary completion date
- Aug 2030
- Lead sponsor
- NYU Langone Health
- Diseases
- Chronic kidney disease
- NCT number
- NCT07741357
What you commit to
- Study type: Interventional
- Planned participants: 280
- From May 2027 to the primary completion date, Aug 2030
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Has received palliative care (inpatient or outpatient) in the last six months.
Other
- Unable to provide informed consent
- Enrolled in hospice
- Has any urgent palliative care needs (i.e. severe pain, emotional distress) identified upon screening. Research staff will be trained to recognize these needs.
- Non-English and Non-Spanish speakers to correspond with the populations most impacted by CKD in the US.
- Pregnant individuals.
Who the study is looking for
- Receive care at nephrology clinics or dialysis centers associated with each site.
- Have CKD stage IV, V (eGFR \< 30 mL/min/1.73m2), or be receiving chronic dialysis
- Speak Spanish or English, and report at IPOS-Renal score of ≥ 3 on a screening survey.
- Willing to be randomized to either study arm and to comply with the study procedures for the assigned group.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.