NCT07744958Not yet recruiting
RESTORE-BLADDER (REgistry on STrategies for Organ pREservation in Muscle-invasive BLADDER Cancer)
Source: ClinicalTrials.gov · Last updated 4 Aug 2026
Brief summary (registry, in English)
Removal of the urinary bladder (radical cystectomy) is a major surgical procedure that can have a permanent impact on a patient's quality of life. Consequently, some patients, despite having received comprehensive counseling and completing systemic therapy, decide against subsequent surgery or alternative radiotherapy. Recent scientific studies suggest that, for selected patients, an attempt at bladder preservation may be a medically justifiable option. However, it remains unclear which patients are truly suitable candidates for bladder-preserving management and which are not. The aim of this registry is therefore to collect and analyze clinical data from this specific patient population.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 30 Jul 2026
- Start date
- Sept 2026
- Primary completion date
- Feb 2029
- Lead sponsor
- Heinrich-Heine University, Duesseldorf
- Diseases
- Bladder cancer
- NCT number
- NCT07744958
What you commit to
- Study type: Observational
- Planned participants: 100
- From Sept 2026 to the primary completion date, Feb 2029
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- No prior preoperative systemic therapy
Age
- Age \< 18 years
Other
- Lack of capacity to provide informed consent
- No histological confirmed muscle-invasive urothelial carcinoma
Who the study is looking for
- Patients aged \>= 18 years, capable of providing informed consent
- Histologically confirmed muscle-invasive urothelial carcinoma of the urinary bladder
- Received perioperative systemic therapy in accordance with current guidelines and subsequently decline cystectomy or radiotherapy
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.