NCT07748247Not yet recruitingPhase 4
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
Desflurane Versus Sevoflurane-Desflurane Swap in Adults Undergoing Bariatric Surgery: A Randomized Non-Inferiority Trial on Extubation Time
Source: ClinicalTrials.gov · Last updated 5 Aug 2026
Brief summary (registry, in English)
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 82 (estimated)
- First submitted
- 24 Jul 2026
- Start date
- 3 Aug 2026
- Primary completion date
- Apr 2027
- Lead sponsor
- Clínica Dávila
- Diseases
- Obesity
- NCT number
- NCT07748247
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 82
- From 3 Aug 2026 to the primary completion date, Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical procedure lasting less than 2 hours.
- Active illicit drug use or substance dependence.
Other illness
- Significant cardiac disease.
- Moderate or severe obstructive respiratory disease, including uncontrolled asthma or chronic obstructive pulmonary disease.
- Known allergy or contraindication to medications used during the intraoperative period.
- Personal or family history of malignant hyperthermia.
- Advanced chronic kidney disease, defined as an estimated glomerular filtration rate below 60 mL/min.
- Myasthenia gravis or another neuromuscular junction disorder.
- Severe cognitive or psychiatric disorder.
Other
- Body mass index greater than 50 kg/m².
- Pregnancy or breastfeeding.
- Refusal to participate or withdrawal of informed consent at any time.
Who the study is looking for
- Age 18 years or older.
- Scheduled for elective laparoscopic gastric bypass surgery.
- Body mass index between 30 and 50 kg/m².
- American Society of Anesthesiologists physical status II or III.
- Able and willing to provide written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clínica Dávila Coordinator of this site? Confirm its status | Santiago | Chile | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.