NCT07748962Recruiting
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these symptoms.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 5 (estimated)
- First submitted
- 27 Jul 2026
- Start date
- 9 Dec 2026
- Primary completion date
- 18 Mar 2027
- Lead sponsor
- The Cleveland Clinic
- Diseases
- Parkinson disease
- NCT number
- NCT07748962
What you commit to
- Study type: Interventional
- Planned participants: 5
- From 9 Dec 2026 to the primary completion date, 18 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis)
- You have been diagnosed with dementia or have difficulty understanding the study or giving consent
- You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate
Other
- You currently have alcohol or substance abuse problems
- You have hearing or vision problems that would make it difficult to use a virtual reality headset
Who the study is looking for
- You have been diagnosed with Parkinson's disease
- You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device
- Your DBS settings have been stable for at least 3 months
- You experience freezing of gait (sudden inability to move your feet when trying to walk)
- You are able to walk on your own for at least 10 minutes without assistance
- You are willing to temporarily stop your Parkinson's medications and have your DBS settings adjusted for study testing
- You are able to understand the study and provide consent to participate
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.