NCT07749027Completed
Comparison Between Low-Dose and High-Dose Nepafenac Sodium
Comparison Between Low-dose and High-dose Nepafenac Sodium in Preventing Macular Edema After Cataract Surgery.
Source: ClinicalTrials.gov · Last updated 6 Aug 2026
Brief summary (registry, in English)
In South Punjab, Pakistan, where tertiary hospitals manage a high cataract workload, data on nepafenac sodium to reduce this inflammatory response is not up to the mark. Relative benefit of low-dose versus high-dose regimens remains unclear in routine clinical practice. Therefore, this study was performed with the objective to compare the effectiveness of low-dose nepafenac sodium with high-dose nepafenac sodium in preventing macular edema after cataract surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 176 (actual)
- First submitted
- 31 Jul 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Muhammad Aamir Latif
- NCT number
- NCT07749027
What you commit to
- Study type: Interventional
- Participants enrolled: 176
- From 1 Jan 2026 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous stroke
- Using topical or systemic anti-inflammatory drugs before surgery
Other illness
- Uncontrolled hypertension
- Diabetes mellitus
- Renal failure
- Ischemic heart disease with unstable symptoms
- History of intraocular surgery
- Hypersensitivity to nepafenac or other non-steroidal anti-inflammatory drugs
Age
- Age-related macular degeneration
Other
- Patients with clinical or optical coherence tomography (OCT) evidence of pre-existing macular edema
- Acute or chronic uveitis
- Retinitis pigmentosa
- Diabetic retinopathy
- Epiretinal membrane
- Retinal vein occlusion
- Glaucoma
- Traumatic cataract
Who the study is looking for
- Any gender
- Aged 18-60 years
- Planned for cataract surgery
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bahawal Victoria Hospital/Quaid-e-Azam Medical College Coordinator of this site? Confirm its status | Bahawalpur | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.