NCT07749287CompletedPhase 3
Use of Hydrogen Sulphide Donor (N-acetyl Cysteine) in Cases With Acute Ischemic Stroke
Assessment of Therapeutic Role of H2S Donor in Acute Myocardial Infarction and Acute Cerebral Ischemia: Comparison in Animal Models and Clinical Cases.
Source: ClinicalTrials.gov · Last updated 6 Aug 2026
Brief summary (registry, in English)
1. Clarify novel systemic and local inflammatory mechanisms underlying the cross talk between brain and heart ischemic states, 2. Investigate the new aspects of NAC beyond traditional therapy, in cerebral and myocardial ischemic conditions, both in animal models and clinical cases.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 121 (actual)
- First submitted
- 13 Jul 2026
- Start date
- 1 Jun 2021
- Primary completion date
- 1 Jan 2023
- Lead sponsor
- Helwan University
- Diseases
- Coronary artery disease, Stroke
- NCT number
- NCT07749287
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 121
- From 1 Jun 2021 to the primary completion date, 1 Jan 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients received thrombolytic
Other illness
- Cerebral haemorrhage
- Dural sinus thrombosis
Age
- Age below 18 years
Other
- Glasgow coma scale (GCS) \< 8
- Post arrest
Who the study is looking for
- Age above 18 years
- AIS patients admitted into stroke unit
- Onset within 48 hours
- Glasgow coma scale (GCS) ≥ 8
- Out of window or contraindicated for thrombolytics
- Not arrested before
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stroke Unit, Neurology Department, Kasr Al Ainy, Cairo University Hospital Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.