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NCT07749690Completed

Mental Rotation and Motor Imagery Training in Multiple Sclerosis

Mental Rotation and Motor Imagery Training for Upper-Extremity Function in Relapsing-Remitting Multiple Sclerosis: A Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 15 Oct 2026

Brief summary (registry, in English)

This randomized controlled trial investigated the effects of sequential laterality, motor imagery, and mental rotation training in individuals with relapsing-remitting multiple sclerosis. Both groups received conventional physiotherapy, while the intervention group received structured cognitive-motor training and the control group received active visual-attention training.

Status (registry)
Completed
Study type
Interventional
Enrollment
56 (actual)
First submitted
30 Jul 2026
Start date
15 Feb 2024
Primary completion date
15 Jan 2026
Lead sponsor
Abant Izzet Baysal University
NCT number
NCT07749690

What you commit to

  • Study type: Interventional
  • Participants enrolled: 56
  • From 15 Feb 2024 to the primary completion date, 15 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Any medication change within the previous 3 months
  • Botulinum toxin injection within the previous 3 months

Other illness

  • Uncorrected severe visual or hearing impairment
  • A communication disorder preventing the perception of or response to the visual and verbal stimuli used in the study
  • Presence of an additional neurological disorder
  • Advanced sensory loss or proprioceptive impairment that could affect participation in the intervention

Other

  • Participation in another structured upper-extremity rehabilitation program or interventional study during the study period

Who the study is looking for

  • Diagnosed with definite relapsing-remitting multiple sclerosis by a neurologist according to the revised McDonald criteria
  • Not experiencing an acute MS relapse
  • Mini Mental State Examination score ≥24
  • No clinical MS relapse within the previous 3 months
  • No corticosteroid treatment for an MS relapse within the previous 3 months
  • Expanded Disability Status Scale score between 1.5 and 6.0
  • Modified Ashworth Scale score ≤2
  • Sufficient communication ability to understand visual and verbal instructions and follow the training protocol
  • Able to attend at least 80% of the planned sessions
  • Able to complete the Movement Imagery Questionnaire-3

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Abant Izzet Baysal University Faculty of Health Science
Coordinator of this site? Confirm its status
BoluTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.