NCT07750015Completed
Derivation and External Validation of the "FORECAST-PC" Prediction Scores
Machine Learning Models Predict 90-Day Functional Outcome in Posterior Circulation Thrombectomy: Derivation and External Validation of the "FORECAST-PC" Prediction Scores
Source: ClinicalTrials.gov · Last updated 6 Aug 2026
Brief summary (registry, in English)
This study aims to develop and externally validate machine learning prediction models (FORECAST-PC) to determine 90-day functional outcomes for patients suffering from acute ischemic stroke in the posterior circulation who are selected for endovascular thrombectomy (EVT)
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 732 (actual)
- First submitted
- 2 Aug 2026
- Start date
- 1 Jan 2015
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Dr. med. Alexander Salerno, MD-PhD
- Diseases
- Stroke
- NCT number
- NCT07750015
What you commit to
- Study type: Observational
- Participants enrolled: 732
- From 1 Jan 2015 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- In-hospital strokes (to avoid the confounding influence of prior systemic comorbidities and the acute event that necessitated initial admission)
- Stroke cases occurring prior to 2015 (to account for major changes in endovascular treatment techniques)
Other illness
- EVT carried out beyond 24 hours from stroke onset
- EVT performed secondarily after in-hospital worsening or stroke recurrence
- Inconsistencies between descriptive dependence status and raw pre-stroke mRS
Other
- Missing primary outcome data
Who the study is looking for
- Age \> 18 years
- Presentation with acute ischemic stroke (AIS) attributed to a radiologically confirmed posterior circulation occlusion
- Selected for Endovascular Thrombectomy (EVT) according to the treating physician
- Pre-stroke modified Rankin Scale (mRS) 0-3
- EVT initiated or attempted within 24-hours of the last known well (LKW) time
- Includes cases with/without prior intravenous thrombolysis (IVT), mothership, and drip-and-ship pathways
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire Vaudois Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.