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NCT07752446Recruiting

Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission

Mediterranean Diet and Time-Restricted Feeding Intervention to Improve Gut Health, Quality of Life and Inflammation in Patients With Ulcerative Colitis in Remission: A Pilot Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 7 Aug 2026

Brief summary (registry, in English)

This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission. Participants will be randomly assigned to one of three groups: a Mediterranean diet, a Mediterranean diet combined with time-restricted feeding (eating within an 8-hour window each day), or standard dietary advice. The Mediterranean diet emphasizes fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting processed foods and red meat. The main outcome will be changes in short-chain fatty acids in stool samples, which are markers of gut health. Additional outcomes include changes in inflammation markers, gastrointestinal symptoms, and quality of life. The results of this study may help identify effective dietary strategies to support patients with ulcerative colitis.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
45 (estimated)
First submitted
22 Apr 2026
Start date
10 Apr 2026
Primary completion date
10 Apr 2027
Lead sponsor
Pontificia Universidad Catolica de Chile
NCT number
NCT07752446

What you commit to

  • Study type: Interventional
  • Planned participants: 45
  • From 10 Apr 2026 to the primary completion date, 10 Apr 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of gastrointestinal surgery
  • Liver or kidney disease
  • Eating disorders

Other

  • Active ulcerative colitis
  • Pregnancy
  • Use of supplements (protein, antioxidants, probiotics)
  • Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP)
  • High levels of physical activity

Who the study is looking for

  • Adults aged 18 to 60 years
  • Diagnosis of ulcerative colitis
  • Clinical remission for at least 6 months
  • Fecal calprotectin \< 250 µg/g in the last 3 months
  • Daily eating window ≥ 11 hours

Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Pontificia Universidad Catolica de Chile
Coordinator of this site? Confirm its status
SantiagoChileRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.