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NCT07754084Not yet recruiting

Comprehensive Clinical Prediction Rule for Acute Heart Failure

Establishing a Comprehensive Clinical Prediction Rule for the Diagnosis of Acute Heart Failure in the Emergency Department

Source: ClinicalTrials.gov · Last updated 11 Aug 2026

Brief summary (registry, in English)

The goal of this prospective observational cohort study is to establish a comprehensive clinical prediction rule integrating clinical characteristics, point-of-care testing (POCT) of NT-proBNP, an 8-point LUS, and a rapid cardiac assessment using bedside echocardiography for diagnosing acute heart failure (AHF) in the emergency department. A clinical prediction rule with high diagnostic accuracy will minimize delays and misdiagnoses, as well as the potential harm they may cause to patients. The primary outcome measure is the adjudicated AHF diagnosis. Secondary outcome measures include ED and discharge diagnosis of the patients.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
560 (estimated)
First submitted
4 Aug 2026
Start date
17 Aug 2026
Primary completion date
31 Dec 2028
Lead sponsor
Chinese University of Hong Kong
NCT number
NCT07754084

What you commit to

  • Study type: Observational
  • Planned participants: 560
  • From 17 Aug 2026 to the primary completion date, 31 Dec 2028
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Trauma patients
  • Pregnancy
  • Unstable patients requiring invasive airway intervention
  • Patients who refuse to participate

Who the study is looking for

  • Adult (aged ≥ 18 years)
  • Suspected AHF or acute dyspnea
  • Symptoms include shortness of breath, swelling of legs, orthopnea, paroxysmal nocturnal dyspnoea, exertional dyspnea or weight gain

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Prince of Wales Hospital
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status
Queen Mary Hospital
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status
Tuen Mun Hospital
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.