Sign in

NCT07754396Completed

Effect of Tranexamic Acid on Bleeding After Bariatric Surgery

Effect of Prophylactic Tranexamic Acid Administration on Perioperative Bleeding and Thromboembolic Outcomes in Patients Undergoing Bariatric Surgery: A Retrospective Observational Cohort Study

Source: ClinicalTrials.gov · Last updated 10 Aug 2026

Brief summary (registry, in English)

Postoperative bleeding is an important complication of bariatric surgery and may lead to increased morbidity, prolonged hospitalization, and higher healthcare costs. Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in several surgical specialties; however, evidence regarding its effectiveness and safety in bariatric surgery remains limited. This retrospective observational cohort study aims to evaluate the effect of prophylactic intraoperative tranexamic acid administration on perioperative bleeding in patients undergoing bariatric surgery. The primary objective is to assess the postoperative decrease in hemoglobin levels. Secondary objectives include evaluating the need for blood transfusion, length of hospital stay, and the incidence of thromboembolic complications, including deep vein thrombosis, pulmonary embolism, portal vein thrombosis, and acute coronary syndrome. The study includes patients who underwent bariatric surgery at G. Gennimatas General Hospital between May 1, 2024, and April 30, 2026.

Status (registry)
Completed
Study type
Observational
Enrollment
140 (actual)
First submitted
31 Jul 2026
Start date
1 May 2024
Primary completion date
30 Apr 2026
Lead sponsor
G.Gennimatas General Hospital
Diseases
Obesity
NCT number
NCT07754396

What you commit to

  • Study type: Observational
  • Participants enrolled: 140
  • From 1 May 2024 to the primary completion date, 30 Apr 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Chronic anticoagulant or antiplatelet therapy.
  • Previous pulmonary embolism.

Other illness

  • Coagulation disorders.
  • Coronary artery disease.
  • Chronic kidney disease.
  • Known hypersensitivity to tranexamic acid.

Other

  • Known thrombophilia.

Who the study is looking for

  • Adults (≥18 years of age).
  • Patients who underwent bariatric surgery at G. Gennimatas General Hospital between May 1, 2024, and April 30, 2026.
  • Availability of complete perioperative and postoperative medical records.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
General Hospital of Athens "G. Gennimatas"
Coordinator of this site? Confirm its status
AthensGreeceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.