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NCT07755501Not yet recruiting

Virtual Reality in Lung Cancer Patients

Effects of Virtual Reality in Lung Cancer Patients Undergoing Immunotherapy and Chemo-immunotherapy

Source: ClinicalTrials.gov · Last updated 12 Aug 2026

Brief summary (registry, in English)

The goal of this randomized clinical trial is to determine whether immersive virtual reality (VR), delivered during scheduled immunotherapy or chemo-immunotherapy infusions, can reduce state anxiety in patients with lung cancer compared with standard care. The main question this study aims to answer is whether participants assigned to the VR group will have a lower mean State-Trait Anxiety Inventory-State score (STAI-Y1) at week 9 than participants assigned to standard care. A total of 60 participants will be randomly assigned in a 1:1 ratio to receive either VR plus standard care or standard care alone. Participants assigned to the VR group will use immersive VR during four infusion visits: at baseline, week 3, week 6, and week 9. Each VR session will begin 15 minutes before the start of the infusion and may continue for the duration of the infusion. The study will also explore the effects of VR on objective tumor response, neutrophil-to-lymphocyte ratio, fatigue, pain, quality of life, dyspnea, and cough. Cybersickness, participant satisfaction, adverse reactions, and study withdrawal will also be assessed.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
5 Aug 2026
Start date
1 Mar 2027
Primary completion date
30 Sept 2027
Lead sponsor
Dott.Claudio Sini
NCT number
NCT07755501

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 1 Mar 2027 to the primary completion date, 30 Sept 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Use of antipsychotic medications
  • Use of illicit drugs or alcohol

Other illness

  • Epilepsy

Who the study is looking for

  • Age older than 18 years
  • Diagnosis of lung cancer with an indication for intravenous immunotherapy or chemo-immunotherapy
  • Montreal Cognitive Assessment (MoCA) score of 26 or higher
  • No significant hearing impairment
  • No significant visual impairment
  • Sufficient ability to read and write in Italian

Age in the registry: 18 months to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Giovanni Paolo II Hospital, Medical Oncology Unit, ASL Gallura
Coordinator of this site? Confirm its status
OlbiaItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.