NCT07758049Completed
Aerobic, Resistance and Inspiratory Muscle Training in Adults With Severe Mental Disorder
Effects of a 12-Week Supervised Multicomponent Exercise Intervention Combining Interval Aerobic Training, Resistance Training and Inspiratory Muscle Training on Cardiorespiratory Fitness, Muscular Strength, Respiratory Function, Body Composition, Adherence and Acceptability in Adults With Severe Mental Disorder: A Single-Arm Study
Source: ClinicalTrials.gov · Last updated 14 Aug 2026
Brief summary (registry, in English)
People with severe mental disorder, such as schizophrenia, bipolar disorder or major depression, tend to have poorer physical health and a shorter life expectancy than the general population. Exercise can help, but it is often difficult to keep up over time. In this study, adults with severe mental disorder took part in a 12-week supervised exercise programme, with two sessions per week. Each session combined stationary cycling, strength exercises on machines, and training of the muscles used for breathing. The programme also included ongoing support and follow-up to help participants keep attending. Fitness, strength, breathing function and body composition were measured before and after the programme. The researchers also recorded how many participants stayed until the end and how often they attended, and interviewed participants about their experience: what motivated them to join, what helped them continue, and what made it difficult. The aim is to find out whether this kind of programme is feasible, safe and acceptable for people with severe mental illness, and what changes it produces in their physical health.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 49 (actual)
- First submitted
- 5 Aug 2026
- Start date
- 9 Sept 2023
- Primary completion date
- 21 Dec 2023
- Lead sponsor
- Universidad Pablo de Olavide
- Diseases
- Schizophrenia
- NCT number
- NCT07758049
What you commit to
- Study type: Interventional
- Participants enrolled: 49
- From 9 Sept 2023 to the primary completion date, 21 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute psychiatric decompensation at the time of enrolment
- Medical condition contraindicating exercise participation, including uncontrolled cardiovascular disease
Other
- Inability to complete baseline assessments
- Currently participating in another structured exercise programme
Who the study is looking for
- Medical diagnosis of severe mental disorder according to ICD-10 criteria
- Aged between 18 and 65 years
- Clinical stability confirmed by the participant's mental health professionals
- Physically able to perform exercise
- Able to travel to the intervention site
- Written informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centro de Investigación en Rendimiento Físico y Deportivo (CIRFD), Universidad Pablo de Olavide Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.