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NCT07759661Not yet recruiting

Innovative 3D Preclinical Models for Mature B-cell Malignancies to Advance Personalized Immuno and Combination Therapies

Source: ClinicalTrials.gov · Last updated 13 Aug 2026

Brief summary (registry, in English)

Adult patients with chronic lymphocytic leukemia (CLL), splenic marginal-zone lymphoma (SMZL) and hairy cell leukemia (HCL) followed at participating clinical sites will be enrolled and undergo sampling of additional amount of blood during the blood draws performed as part of standard clinical care. The project aims to develop and validate innovative patient-derived 3D bioprinted models that faithfully reproduce the key microenvironments of lymphoid tissues, enabling a more physiologically relevant study of mature B-cell malignancies.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
64 (estimated)
First submitted
7 Aug 2026
Start date
Nov 2026
Primary completion date
Nov 2029
Lead sponsor
IRCCS San Raffaele
NCT number
NCT07759661

What you commit to

  • Study type: Observational
  • Planned participants: 64
  • From Nov 2026 to the primary completion date, Nov 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \- Participant is unable or unwilling to provide informed consent for participation in the study

Who the study is looking for

  • Age ≥18 years
  • Diagnosis of CLL, SMZL or HCL
  • Participant is willing and able to autonomously give informed consent for participation in the study.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS Ospedale San Raffaele
Coordinator of this site? Confirm its status
MilanItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.