NCT07760155Not yet recruitingPhase 2
A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody, ESG206, in Patients With Systemic Lupus Erythematosus
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
This is a multicenter, randomized, double-blind, placebo-controlled Phase II study designed to evaluate the efficacy and safety of ESG206 in participants with Systemic Lupus Erythematosus (SLE).
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 7 Aug 2026
- Start date
- Sept 2026
- Primary completion date
- Mar 2028
- Lead sponsor
- Shanghai Escugen Biotechnology Co., Ltd
- Diseases
- Lupus (SLE)
- NCT number
- NCT07760155
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 40
- From Sept 2026 to the primary completion date, Mar 2028
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior or recent use of prohibited immunomodulatory therapies
Other illness
- Have other autoimmune diseases that may interfere with the assessment of SLE
- Clinically significant infections, malignancies, or uncontrolled medical conditions
Other
- Pregnancy or breastfeeding
Who the study is looking for
- Adults (≥18 years of age) with a confirmed diagnosis of Systemic Lupus Erythematosus
- Evidence of active disease at screening
- Willing and able to provide written informed consent
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Changde First People's Hospital Coordinator of this site? Confirm its status | Changde | China | Unknown status |
| Xiangya Hospital Central South University Coordinator of this site? Confirm its status | Changsha | China | Unknown status |
| Second Affiliated Hospital of Guilin Medical University Coordinator of this site? Confirm its status | Guilin | China | Unknown status |
| Affiliated Hospital of Hebei Engineering University Coordinator of this site? Confirm its status | Handan | China | Unknown status |
| Huzhou third people's Hospital Coordinator of this site? Confirm its status | Huzhou | China | Unknown status |
| Jinhua Municipal Central Hospital Coordinator of this site? Confirm its status | Jinhua | China | Unknown status |
| Linfen Central Hospital Coordinator of this site? Confirm its status | Linfen | China | Unknown status |
| Liupanshui Shougang Shuigang Hospital Coordinator of this site? Confirm its status | Liupanshui | China | Unknown status |
| Loudi Central Hospital Coordinator of this site? Confirm its status | Loudi | China | Unknown status |
| Mianyang Central Hospital Coordinator of this site? Confirm its status | Mianyang | China | Unknown status |
| Affiliated Hospital of North Sichuan Medical College Coordinator of this site? Confirm its status | Nanchong | China | Unknown status |
| Ningbo Medical Center Lihuili Hospital Coordinator of this site? Confirm its status | Ningbo | China | Unknown status |
| Renji Hospital Shanghai Jiao Tong University School of Medicine Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| Shanghai Tongji Hospital Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| Shenzhen Third People's Hospital Coordinator of this site? Confirm its status | Shenzhen | China | Unknown status |
| Second Hospital of Hebei Medical University Coordinator of this site? Confirm its status | Shijiazhuang | China | Unknown status |
| Xuzhou Central Hospital Coordinator of this site? Confirm its status | Xuzhou | China | Unknown status |
| Zhongshan Traditional Chinese Medicine Hospital Coordinator of this site? Confirm its status | Zhongshan | China | Unknown status |
| Zhuzhou Central Hospital Coordinator of this site? Confirm its status | Zhuzhou | China | Unknown status |
| Zibo Central hospital Coordinator of this site? Confirm its status | Zibo | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.