NCT07764939Active, not recruiting
Comparative Effects of CIMT and TOT on Hand Function Recovery in Post Stroke Patients
Comparative Effects of Constraint Induced Movement Therapy and Task-oriented Training on Hand Function Recovery in Post Stroke Patients
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
This controlled clinical study investigates and compares the effectiveness of CIMT and TOT in improving hand function among post-stroke patients. A total of 48 participants from hospitals in Sialkot will be randomly divided into two groups and receive a 3-week intervention consisting of 15 sessions. Outcomes will be assessed using the 9-Hole Peg Test, Jebsen-Taylor Hand Function Test, and grip strength, and the data will be analyzed using SPSS-21 under a single-blinded design.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 48 (actual)
- First submitted
- 1 Jun 2026
- Start date
- 12 Jul 2025
- Primary completion date
- Oct 2026
- Lead sponsor
- Riphah International University
- Diseases
- Stroke
- NCT number
- NCT07764939
What you commit to
- Study type: Interventional
- Participants enrolled: 48
- From 12 Jul 2025 to the primary completion date, Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Recurrent or bilateral stroke
- Severe upper limb impairment
- Active infections, skin lesions, or wounds on the upper limb
Other
- Severe spasticity (Modified Ashworth Scale \> 3) or joint contractures
- Severe aphasia, neglect, or cognitive impairments affecting task performance
- Joint contractures or orthopedic limitations in the upper limb
- Severe pain during limb movement
- Participation in other upper limb rehabilitation programs concurrently
Who the study is looking for
- Age between 45 and 65 years
- Both male and female participants
- First-ever unilateral ischemic or hemorrhagic stroke confirmed by imaging
- Stroke onset in subacute to chronic phase (\>3 months post-stroke)
- Medically stable and able to sit independently
- Voluntary wrist extension of at least 10 degrees and finger extension of at least 10 degrees in the affected hand
- Mini-Mental State Examination (MMSE) score \> 26
- No significant pain or spasticity in affected upper limb (Modified Ashworth Scale \< 2)
- Adequate sitting balance and trunk control for upper limb activities
- Willingness and availability to complete the full intervention (3 weeks)
- No significant musculoskeletal impairments (e.g., fractures or arthritis) affecting the upper limb
Age in the registry: 45 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| department of physiotherapy, Allama Iqbal Memorial Teaching Hospital Coordinator of this site? Confirm its status | Sialkot | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.