NCT07768137Not yet recruiting
Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With Stroke
Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With Stroke: a Randomized Controlled Pilot Trial
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
Neurogenic overactive bladder (nOAB) is a common and distressing sequela following stroke, significantly impairing quality of life and imposing a substantial financial burden. Existing pharmacological options often present adverse effects, while standard non-pharmacological treatments, such as pelvic floor muscle training (PFMT), face compliance and efficacy limitations in individuals with functional impairments. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique capable of modulating neuronal excitability and cortical plasticity. Targeting the supplementary motor area (SMA) via tDCS may regulate pelvic floor muscle (PFM) and detrusor activities. However, clinical evidence evaluating tDCS as an adjuvant to PFMT for stroke survivors with nOAB is lacking. This randomized controlled pilot trial aims to evaluate the feasibility, preliminary effectiveness, and cost-utility of active tDCS combined with PFMT compared to sham tDCS plus PFMT in stroke survivors suffering from nOAB.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 2 Aug 2026
- Start date
- 10 Nov 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- The Hong Kong Polytechnic University
- Diseases
- Stroke
- NCT number
- NCT07768137
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 10 Nov 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- (1) a personal or family history of epilepsy or seizures; (2) metallic implants or implanted electronic devices in or near the head, including cochlear implants, intracranial shunts, deep brain stimulation electrodes, surgical clips, staples, or other cranial metallic implants; (3) a cardiac pacemaker or other implanted electronic medical device; (4) increased intracranial pressure, an intracranial tumour, skull abnormalities, previous significant brain injury, or previous brain surgery; (5) skin lesions, infection, broken skin, or marked skin sensitivity at the electrode-placement sites; (6) frequent or severe headaches; (7) serious or unstable medical conditions, or use of medications that may affect brain excitability; (8) a history of substantial alcohol or substance misuse; (9) pregnancy or possible pregnancy; or (10) have received non-invasive brain stimulation (e.g., transcranial direct current stimulation, repetitive transcranial magnetic stimulation, and transcranial alternating current stimulation) before.
Who the study is looking for
- (1) Aged between 18-80 years; (2) having overactive bladder (OAB) symptoms (such as urgency, urine leakage, frequent urination, or frequent night-time urination) after stroke; (3) experiencing moderate (scoring 6-11 points on the Overactive Bladder Symptom Score \[OABSS\]) to severe OAB (scoring ≥ 12 points on OABSS); and (4) obtaining a Mini-Mental State Examination (MMSE) score of ≥ 24.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hong Kong Polytechnic University Coordinator of this site? Confirm its status | Hong Kong | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.