NCT07768683Completed
Stroke Upper Limb Rehabilitation With Robot Operators: a Synergistic Approach for Human-Robot Interaction and Rehabilitative Trials.
Riabilitazione Dell'Arto Superiore in Soggetti Con Esiti di Ictus Con Dispositivi Robotizzati: un Approccio Sinergico Per Valutare l'Interazione Uomo-robot e Gli Effetti Dell'Intervento Riabilitativo
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
In clinical scenario, clinical scales and kinematic analysis are usually used for the evaluation of patients. However, these methods are limited, since they may suffer from the lack of objectivity and sensitivity. Synergies go beyond pure kinematics and allow to directly understand the neural mechanisms underlying the motor impairment. Synergy analysis has been exploited for understanding physiological mechanisms in healthy subjects, but only few studies analyzed muscle synergies on patients during rehabilitation. In order to translate this methodology to the clinical practice, there is the need of comprehensive and structured studies. However, only few pilot studies are available that analyzed synergies during rehabilitation. Thus, in this study we aimed at filling this gap by analyzing synergies during human-robot interaction when using an end-effector robot and an exoskeleton robot and by assessing in detail the modifications of synergies after robotic rehabilitation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 5 Aug 2026
- Start date
- 8 May 2025
- Primary completion date
- 12 May 2026
- Lead sponsor
- Villa Beretta Rehabilitation Center
- Diseases
- Stroke
- NCT number
- NCT07768683
What you commit to
- Study type: Interventional
- Participants enrolled: 50
- From 8 May 2025 to the primary completion date, 12 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe psychiatric disorder
- Permanent neurologic symptoms present immediately before stroke
- Physical conditions that can alter normal biomechanics (e.g., recent sprains or injuries, etc.)
- Unstable medical condition
Other
- Subjects with a high level of spasticity (Modified Ashworth Scale: In general \>3 except for motorized joints which may be \>2)
- Pain in the affected upper limb (Numeric Rating Scale \> 6)
- Pregnant or nursing women
- No written informed consent from the patient or the legal representative
- Active implantable devices (e.g., pacemaker)
Who the study is looking for
- Adult subjects (aged ≥18 years old)
- Non orthopaedic condition at upper limb
- No neurological or motor impairment Exclusion criteria for healthy subjects
- Physical conditions that can alter normal biomechanics
- Pregnant or nursing women
- No written informed consent
- Active implantable devices (e.g., pacemaker)
- Adult subjects (aged ≥18 years old)
- Subjects suffering from subacute and/or chronic stroke disability
- Coming from ischemic or hemorrhagic stroke
- With a level of motor impairment defined by a minimum residual motion corresponding to Motricity Index ≥ 39.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Villa Beretta Rehabilitation Center Coordinator of this site? Confirm its status | Costa Masnaga | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.