NCT07770776Active, not recruiting
Short Term Effects of Early Respiratory Muscle Training on Respiratory Muscle Strength in Inpatient Acute Stroke
Short-Term Effects of Early Combined High-Intensity Interval Inspiratory and Expiratory Muscle Training on Respiratory Muscle Strength in Inpatients With Acute Stroke
Source: ClinicalTrials.gov · Last updated 18 Aug 2026
Brief summary (registry, in English)
This study aims to determine the early effectiveness of combined high-intensity interval inspiratory and expiratory muscle training in hospitalized patients with acute stroke. Participants will be assigned to receive either combined high-intensity interval inspiratory and expiratory muscle training or conventional diaphragmatic breathing exercises. The main questions this study aims to answer are whether the combined high-intensity interval inspiratory and expiratory muscle training can improve: * inspiratory muscle strength, measured using maximal inspiratory pressure; * expiratory muscle strength, measured using maximal expiratory pressure; * chest expansion, measured using thoracic expansion; and * the ability to sustain speech on a single breath, measured using the single-breath count test. Researchers will compare changes before and after the intervention between the two groups to determine whether combined high-intensity interval inspiratory and expiratory muscle training provides greater early improvement than conventional diaphragmatic breathing exercises in hospitalized patients with acute stroke.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 13 Aug 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 5 Sept 2026
- Lead sponsor
- Prof. R. D. Kandou General Hospital
- Diseases
- Stroke
- NCT number
- NCT07770776
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 1 Apr 2026 to the primary completion date, 5 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous participation in or experience with a respiratory muscle training program.
- History of major thoracic or abdominal surgery within the previous 3 months.
Other illness
- Resting heart rate \<40 beats/min or \>110 beats/min.
- Presence of chronic pulmonary disease.
- Presence of unstable cardiac disease.
- Presence of another neurological disorder associated with respiratory dysfunction.
- Presence of an orthopedic or musculoskeletal condition that significantly interferes with respiratory function or the ability to perform respiratory muscle training.
Other
- Resting blood pressure \>160/100 mmHg.
- Resting peripheral oxygen saturation (SpO₂) \<92%.
- Fever, defined as body temperature ≥37.5°C.
- Presence of a tracheostomy tube.
Who the study is looking for
- Male or female participants aged 18 years or older.
- First-ever acute ischemic stroke, with stroke onset 2 to 14 days before enrollment, confirmed by computed tomography (CT) or magnetic resonance imaging (MRI).
- National Institutes of Health Stroke Scale (NIHSS) score ≥5, with the presence of hemiparesis.
- Baseline maximal inspiratory pressure (MIP) \<80 cmH₂O.
- Baseline maximal expiratory pressure (MEP) \<68 cmH₂O.
- Able to understand instructions and participate in the respiratory muscle training program.
- Willing to comply with the study protocol and provide written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Prof. R. D. Kandou General Hospital Coordinator of this site? Confirm its status | Manado | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.