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NCT07771673Not yet recruiting

Multi-Omic SignAtures of Inflammatory Cutaneous Diseases

Source: ClinicalTrials.gov · Last updated 18 Aug 2026

Brief summary (registry, in English)

The goal of this observational study is to identify the immune profile underlying various inflammatory skin diseases, through multi-omic procedures. The main questions it aims to answer are: 1. What are the molecular and immune signatures of individuals with inflammatory skin disease? 2. Can these signatures reveal potential therapeutic targets for individuals with inflammatory skin disease? 3. How do patients' multi-omic signatures change before and after receiving systemic therapy? 4. Can the samples and data collected through this study provide a valuable bioresource for future skin disease research?

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
400 (estimated)
First submitted
10 Aug 2026
Start date
Sept 2026
Primary completion date
Jul 2031
Lead sponsor
Guy's and St Thomas' NHS Foundation Trust
NCT number
NCT07771673

What you commit to

  • Study type: Observational
  • Planned participants: 400
  • From Sept 2026 to the primary completion date, Jul 2031
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Participants who have received topical corticosteroids to sites of biopsies (inflamed area of skin) for at least 2 weeks prior to tissue sampling.
  • Enrolment in any interventional study with systemic treatment within 3 months prior to baseline biopsy.

Other

  • Inability to give written informed consent.
  • Inability to participate in study-specific procedures.
  • Participants who are pregnant (confirmed on a positive urine pregnancy test) or breastfeeding

Who the study is looking for

  • Able to provide written informed consent prior to performing any protocol-related procedures, including screening.
  • Adults (≥18 years) with confirmed diagnosis of inflammatory skin disease (defined as any skin disease with an inflammatory component, including but not limited to, genetic skin disease, such as EB), OR
  • Adults age (≥18 years) without skin or systemic disease.

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.