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NCT07771699Recruiting

Cross-modal Neuromodulation to Improve Balance and Cognition in Older Adults With Glaucoma: A Randomized Trial of Cerebellar Transcranial Electrical Stimulation

Source: ClinicalTrials.gov · Last updated 18 Aug 2026

Brief summary (registry, in English)

The goal of this clinical trial is to use different tES techniques to constantly stimulate the cerebellum in older glaucoma patients. The main questions aim to answer : 1. If the different types of tES targeting the cerebellum can modulate glaucoma patients' balance function and visual-cognitive function? 2. Which tES techniques among the two types can benefit most? Participants will be required to receive the stimulation 15 times (3 sessions, 5 continuous days/session, 1-week interval between each session), and complete the balance and visual-cognitive function outcome measurements before and after each session.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
36 (estimated)
First submitted
28 Jul 2026
Start date
1 Jul 2026
Primary completion date
1 Nov 2029
Lead sponsor
The Hong Kong Polytechnic University
Diseases
Glaucoma
NCT number
NCT07771699

What you commit to

  • Study type: Interventional
  • Planned participants: 36
  • From 1 Jul 2026 to the primary completion date, 1 Nov 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Have musculoskeletal disorders or neurological diseases that can affect the balance or nervous system.

Age

  • Ocular diseases other than glaucoma (e.g., age-related macular degeneration, diabetic retinopathy, moderate to severe cataract) or severe hearing impairment (to ensure that participants can hear the instructions clearly during assessments and training)

Other

  • Have any contraindications for tES

Who the study is looking for

  • Age over 55 years old;
  • Diagnosis of primary open-angle or normal-tension glaucoma with relative scotoma in both eyes;
  • Humphrey Field Analyzer visual field loss (mean deviation of ≤- 6 dB) using the 24-2 testing protocol for both eyes;
  • Best-corrected distance visual acuity of 6/12 (equivalent to 0.3 logMAR) or better;
  • Cognitive functional score of 22 or above in the Montreal Cognitive Assessment -Hong Kong version (HK-MoCA).
  • Only the right-handed population will be recruited (screening by the Edinburgh Handedness Inventory).

Age in the registry: 55 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hong Kong Polytechnic University
Coordinator of this site? Confirm its status
KowloonHong Kong SAR ChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.