NCT07773272Recruiting
Cardiovascular-kidney-metabolic (CKM)-Guided Therapy for Patients After Acute Coronary Syndrome
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
Patients with a history of myocardial infarction are at significantly increased risk of recurrent cardiovascular events. Despite established clinical guidelines, secondary preventive care is often initiated too late, inadequate in intensity or incomplete in application. As a result, important opportunities to prevent serious outcomes are missed. The aim of this project is to investigate whether rapid, guideline-based treatment following myocardial infarction leads to improved patient outcomes. The study protocol is based on current clinical guidelines and targets key domains including diabetes, hypertension, and hypercholesterolemia. Outcomes of patients treated according to the study protocol will be compared to those receiving standard care. Primary endpoints include major adverse cardiac- and cerebrovascular events within a 24-month follow-up period. The investigators hypothesize that rapid, guideline-based intervention will result in improved risk factor management, leading to a reduction in cardiovascular events and mortality. For patients, this may translate into improved health, quality of life and life expectancy. This project aims to deliver a practical protocol for effective secondary prevention in clinical practice, which is expected to reduce healthcare utilization in the long term. With this initiative, the investigators seek to take a significant step toward improving post-myocardial infarction care and contributing to sustainable cardiovascular healthcare.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1215 (estimated)
- First submitted
- 30 Jul 2026
- Start date
- Mar 2026
- Primary completion date
- Mar 2029
- Lead sponsor
- Zuyderland Medisch Centrum
- NCT number
- NCT07773272
What you commit to
- Study type: Observational
- Planned participants: 1215
- From Mar 2026 to the primary completion date, Mar 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute coronary syndrome secondary to other diseases
Other
- Life expectancy \< 1 year based on the clinician's expertise
Who the study is looking for
- Age \> 18 years
- Hospitalised with acute coronary syndrome
- Underwent percutaneous coronary intervention
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiology Coordinator of this site? Confirm its status | Heerlen | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.