NCT07773766Not yet recruiting
Prevalence of Fibromyalgia in Patients With Plaque Psoriasis
Fibromyalgia in Patients With Plaque Psoriasis - Assiut University Hospital
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
This observational study aims to determine how common fibromyalgia syndrome and central sensitization are in adults with plaque psoriasis compared to healthy individuals. Plaque psoriasis is a chronic inflammatory skin disease that can affect the entire body, which may increase the risk of developing chronic pain conditions. Fibromyalgia causes widespread musculoskeletal pain, fatigue, and sleep disturbances, while central sensitization involves the central nervous system becoming highly sensitive to pain. Researchers will evaluate 55 adult patients diagnosed with plaque psoriasis and 55 age- and sex-matched healthy volunteers at the Dermatology Outpatient Clinic at Assiut University Hospital. Participants will undergo a clinical examination to assess their psoriasis severity and will complete standardized questionnaires to evaluate pain intensity, fibromyalgia symptoms, central sensitization, and overall quality of life. The findings of this study may help doctors better understand these overlapping conditions to improve the early identification and management of pain in patients with psoriasis.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 110 (estimated)
- First submitted
- 14 Aug 2026
- Start date
- Sept 2026
- Primary completion date
- Sept 2027
- Lead sponsor
- Assiut University
- Diseases
- Psoriasis
- NCT number
- NCT07773766
What you commit to
- Study type: Observational
- Planned participants: 110
- From Sept 2026 to the primary completion date, Sept 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with previously diagnosed major depressive disorder or generalized anxiety disorder.
Other illness
- Patients with other diagnosed rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis).
- Patients with uncontrolled diabetes mellitus, heart failure, renal failure, or thyroid disorders.
- History of malignancy.
Other
- Patients with psoriatic arthritis or other inflammatory arthritis.
- Current use of antidepressants, anticonvulsants, or benzodiazepines.
- Pregnancy.
Who the study is looking for
- Adult patients (≥18 years) with clinically diagnosed plaque psoriasis.
- Both males and females.
- Willing to participate and provide written informed consent.
- For controls: Apparently healthy age- and sex-matched volunteers.
- For controls: No history of psoriasis, psoriatic arthritis, or other chronic inflammatory or rheumatic diseases.
- For controls: Willing to participate and provide written informed consent.
Age in the registry: 18 years to - · Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.