NCT07774286Not yet recruiting
Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine
Multi-segmental Spinal Manual Therapy for Pain, Central Sensitization, and Sensorimotor Control in Women With Episodic Migraine: A Case Series.
Source: ClinicalTrials.gov · Last updated 25 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the clinical effects of multi-segmental spinal manual therapy on pain intensity, central sensitization (CS), and sensorimotor control in women diagnosed with episodic migraine (EM). Participants receive 10 sessions of a comprehensive manual therapy intervention targeting the cervical, thoracic, lumbar, and sacral regions over a 2-week period. Clinical outcomes-including headache pain intensity, sensorimotor dysfunction, headache-related disability, and cutaneous allodynia-are evaluated at baseline, immediately after the 2-week treatment, and at a 1-month follow-up. This study aims to investigate whether addressing multiple spinal segments with manual therapy improves clinical symptoms, spinal motor control, and central pain processing in female individuals with EM.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 16 Aug 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Borna Farhoomand
- Diseases
- Migraine
- NCT number
- NCT07774286
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 1 Sept 2026 to the primary completion date, 30 Nov 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having received physical therapy within the last 3 months,
- Receiving any prophylactic or interventional migraine therapy other than acute analgesics,
Other illness
- History of communication disorders or neuromusculoskeletal diseases that impede assessment procedures,
- Diagnosis of fibromyalgia syndrome or myofascial pain syndrome,
- Diagnosis of systemic rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus),
- Diagnosis or presence of symptoms related to spinal disc disorders (e.g., disc herniation, disc prolapse),
- History of whiplash or similar cervical/head trauma,
- Self-reported history or presence of malignancy.
Other
- Headache frequency exceeding 15 days per month,
- Diagnosis of other primary or secondary headache types (e.g., cervicogenic headache, tension-type headache),
- Pregnancy,
- Diagnosis or presence of symptoms associated with temporomandibular joint dysfunction (TMD),
- Having undergone anesthetic nerve block procedures within the last 6 months,
Who the study is looking for
- Female patients aged 18-30 years,
- Diagnosis of episodic migraine established by a specialist neurologist,
- Headache frequency of \<15 days per month,
- Pain intensity score of ≥40 mm on the Visual Analog Scale (VAS),
- Absence of any diagnosed psychiatric disorders,
- Literacy (ability to read and write),
- Ability to communicate effectively without language or cognitive barriers,
- Voluntary participation confirmed by signed written informed consent.
Age in the registry: 18 years to 30 years · Sex: Female · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.