NCT07776262Recruiting
Safety and Efficacy of Cryoablation for Thyroid Tumors
Study on the Safety and Efficacy of Cryoablation Therapy for Thyroid Tumors
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
The goal of this clinical study is to learn if cryoablation works to treat thyroid tumors. It will also learn about the safety of cryoablation for thyroid tumors. The main questions it aims to answer are: * Does cryoablation shrink thyroid tumors over time? * What side effects or problems do participants have after cryoablation? Participants will receive cryoablation treatment guided by ultrasound. Researchers will track tumor size changes and check for any safety issues during follow-up visits.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 108 (estimated)
- First submitted
- 13 Aug 2026
- Start date
- 9 Feb 2026
- Primary completion date
- 10 Jan 2030
- Lead sponsor
- Yukun Luo
- Diseases
- Thyroid cancer, Childhood cancers
- NCT number
- NCT07776262
What you commit to
- Study type: Interventional
- Planned participants: 108
- From 9 Feb 2026 to the primary completion date, 10 Jan 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- (1) Biopsy confirms high-risk subtype papillary thyroid carcinoma; (2) History of thyroid surgery or radiotherapy; (3) Complicated with malignant tumors in other sites; (4) Severe coagulation dysfunction, or patients taking oral anticoagulants who have not reached the required drug-withdrawal period; (5) Incomplete follow-up data. 【Group 2: Benign thyroid nodule patients】
- Patients with uncorrected psychiatric disorders or consciousness disturbance who cannot cooperate with treatment;
- Patients with neck extension disorders of various causes who cannot cooperate with treatment;
- Severe coagulation dysfunction, or patients taking oral anticoagulants who have not completed the required drug withdrawal period;
- Severe cardiopulmonary insufficiency and inability to lie supine for the procedure;
- Unrecovered recurrent laryngeal nerve injury contralateral to the lesion.
Other
- 【Group 1: Papillary Thyroid Carcinoma (PTC) patients】
Who the study is looking for
- 【Group 1: Papillary Thyroid Carcinoma (PTC) patients】
- Pre-operative ultrasound evaluation shows the maximum tumor diameter \<1 cm;
- Papillary thyroid carcinoma (PTC) confirmed by ultrasound-guided fine-needle aspiration (FNA) biopsy;
- Solitary PTC confirmed by pre-operative ultrasound;
- Imaging examinations demonstrate no extrathyroidal invasion, cervical lymph node metastasis or distant metastasis.
- 【Group 2: Benign thyroid nodule patients】
- Benign nodule confirmed by puncture biopsy;
- Preoperative ultrasound confirms solid nodule with maximum diameter greater than 2 cm;
- Patients refuse surgical treatment or cannot tolerate surgery, voluntarily receive thyroid ablation therapy and sign the informed consent form.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese People's Liberation Army General Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.