NCT07777419Recruiting
Impact of Subthalamic Nucleus Deep Brain Stimulation on COGnitive and PSYchiatric Symptoms in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 4 Sept 2026
Brief summary (registry, in English)
With this study, the investigators want to investigate how deep brain stimulation (DBS) affects various cognitive and psychiatric symptoms of Parkinson's disease (PD). In particular, they will examine whether stimulation of the left hemisphere has a different effect than stimulation of the right hemisphere on cognitive and psychiatric symptoms.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 13 Aug 2026
- Start date
- 1 Aug 2026
- Primary completion date
- 31 Jul 2028
- Lead sponsor
- Insel Gruppe AG, University Hospital Bern
- Diseases
- Parkinson disease
- NCT number
- NCT07777419
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 1 Aug 2026 to the primary completion date, 31 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other disease affecting the brain (e.g. Alzheimer's disease, vascular dementia, multiple sclerosis, stroke, traumatic brain injury, non-provoked epilepsy, brain tumour, etc.)
- Haemorrhage during implantation of STN-DBS, which resulted in permanent cognitive or physical impairment
- Schizophrenia, ongoing substance abuse, bipolar disorder or autism
- For part II: Severe depressive disorder and/or suicidality
Other
- Atypical Parkinsonism
- Insufficient quality or lack of brain imaging data pre and/or post STN-DBS
Who the study is looking for
- Diagnosed with Parkinson's disease
- Treated with subthalamic nucleus deep brain stimulation (STN-DBS)
- For part I: General research consent for the analysis of routine clinical data
- For part II of the study: ability to provide informed consent
- native German or French speaker
- Montreal Cognitive Assessment with score ≥ 20
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Inselspital, Berne Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.