NCT07780175Active, not recruiting
Intradialytic Exercise and Cognitive Function
The Effects of Long-Term Hybrid Intradialytic Exercise on Cognitive Function and Quality of Life in End-Stage Kidney Disease Patients: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
Exercise training may improve global and domain-specific cognitive function, mental health, psychological well-being, dialysis efficacy, and health-related quality of life in people with end-stage kidney disease receiving hemodialysis. Intradialytic exercise is considered feasible, safe, and effective in this population. This randomized controlled trial will compare standard care alone with three intradialytic exercise modalities--resistance training, aerobic training, and combined hybrid training--to examine short- and longer-term effects on cognitive function and quality of life in hemodialysis patients.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 15 Jul 2026
- Start date
- 15 Jul 2026
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- University of Thessaly
- Diseases
- Chronic kidney disease
- NCT number
- NCT07780175
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 15 Jul 2026 to the primary completion date, 1 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Terminal illness with life expectancy shorter than the 6-month intervention/follow-up period.
- Clinically unstable condition as determined by the treating clinical team.
- Diagnosis of dementia, Alzheimer disease, or severe cognitive dysfunction, defined as a Mini-Mental State Examination score below 17 points.
Other
- Newly established on hemodialysis for less than 3 months.
- Pregnancy at baseline or at any point during the intervention.
- Physical complication or limitation that prevents safe participation in exercise training.
Who the study is looking for
- Able to provide written informed consent.
- Chronic kidney disease stage 5 / end-stage kidney disease.
- Established on maintenance hemodialysis for at least 3 months.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| School of Life and Health Sciences Coordinator of this site? Confirm its status | Nicosia | Cyprus | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.